Managing electrical stimulation therapy based on variable electrode combinations

• US 8,996,123 B2
• Filed: 10/18/2010
• Issued: 03/31/2015
• Est. Priority Date: 10/21/2009
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Goetz, Steven M., Davis, Jon P., Torgerson, Nathan A., Gokaldas, Shyam, Singal, Ashish, Sahasrabudhe, Rajeev M., Huhta, Brent A.
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): GHAND, JENNIFER LEIGH-STEWAR
• Application Number:
  US12/906,418
• Publication Number:
  US 20110093030A1
• Time in Patent Office: 1,625 Days
• Field of Search: 607/59, 607/17
• US Class Current: 607/59
• CPC Class Codes: A61N 1/0553 Paddle shaped electrodes, e.g. for laminotomy
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means

Abstract

Various programming techniques are described for medical devices that deliver electrical stimulation therapy that may include mapping between discrete electrical stimulation parameters and a graphical view of the electrical stimulation representing a stimulation zone generated by the parameters. In one example, a method includes receiving, via a programmer for an electrical stimulator, user input that graphically manipulates at least one of size and a shape of a graphical representation of at least one electrical stimulation zone displayed on the programmer, and defining a program to control delivery of electrical stimulation therapy based on the user input.

Claims

1. A programmer for an implantable electrical stimulator, the programmer comprising:

a user interface that displays a graphical representation of at least one electrical stimulation zone and receives user input graphically manipulating at least one of a size and a shape of the representation of the at least one electrical stimulation zone; and

a processor configured to define a program to control delivery of electrical stimulation therapy by the implantable electrical stimulator based on the user input, wherein the processor is configured to;

define an intensity of the at least one electrical stimulation zone;

define each of a plurality of electrodes, on at least one lead, to deliver at least a portion of the electrical stimulation therapy;

automatically determine an electrical stimulation contribution of each of the plurality of defined electrodes to the at least one stimulation zone; and

automatically determine a stimulation amplitude of the portion of the electrical stimulation therapy delivered by each of the plurality of defined electrodes based on the electrical stimulation contribution of the electrode and the intensity of the at least one electrical stimulation zone, wherein the amplitude of at least one of the plurality of defined electrodes is equal to an amplitude corresponding to the intensity of the at least one electrical stimulation zone, and wherein a sum of the amplitudes of the plurality of defined electrodes is greater than the amplitude corresponding to the intensity of the at least one electrical stimulation zone.

2. The programmer of claim 1, wherein the user input comprises stretching the representation of the at least one stimulation zone.

3. The programmer of claim 1, wherein the user input further comprises moving the representation of the at least one stimulation zone from a first location on a display to a second location on the display.

4. The programmer of claim 1, wherein the user interface further receives user input that defines the intensity of the at least one electrical stimulation zone.

5. The programmer of claim 1, wherein the processor is configured to control at least one of a rate of change of a stretch of the at least one stimulation zone and a rate of change of a move of the at least one stimulation zone.

6. The programmer of claim 1, wherein the processor is further configured to:

generate an electrical stimulation amplitude to be delivered by an electrode carried by a housing of the implantable electrical stimulator based on a sum of the electrical stimulation amplitudes of the plurality of defined electrodes.

7. The programmer of claim 6, wherein the processor is further configured to:

modify the electrical stimulation amplitude to be delivered by the electrode carried by the housing of the implantable electrical stimulator in response to at least one of the user interface receiving user input graphically defining a representation of another electrical stimulation zone, the at least one electrical stimulation zone moving, and the at least one electrical stimulation zone stretching.

8. The programmer of claim 1, wherein the processor is further configured to:

compare the determined electrical stimulation contribution of each of the plurality of defined electrodes to a threshold value; and

determine whether each of the plurality of defined electrodes will be used to deliver at least a portion of the electrical stimulation therapy based on the comparison.

9. The programmer of claim 1, wherein the processor is further configured to:

generate and display to a user an indication of zone extent based upon at least one of the defined electrodes.

10. The programmer of claim 9, wherein the indication of zone extent displayed to the user provides a visual indication of a relative electrical stimulation contribution of the at least one of the defined electrodes to the at least one stimulation zone.

11. The programmer of claim 1, wherein the user interface further receives at least one of user input that moves the representation of the at least one electrical stimulation zone, and user input that stretches the representation of the at least one electrical stimulation zone.

12. The programmer of claim 1, wherein at least two of the plurality of defined electrodes are the same polarity.

13. The programmer of claim 1, wherein the processor is further configured to multiply the electrical stimulation contribution by the amplitude corresponding to the intensity of the at least one electrical stimulation zone to determine the stimulation amplitude of each of the plurality of electrodes within the at least one stimulation zone, wherein the electrode stimulation contribution of at least one of the plurality of defined electrodes is 1.0, and wherein the electrode contribution of a second of the plurality of defined electrodes is greater than 0.0 and less than 1.0.

14. The programmer of claim 1, wherein the processor is further configured to control an implantable medical device to deliver stimulation with the plurality of defined electrodes based on the defined stimulation amplitudes.

15. A method comprising:

receiving, via a programmer device for an electrical stimulator, user input that graphically manipulates at least one of a size and a shape of a graphical representation of at least one electrical stimulation zone displayed on the programmer;

defining an intensity of the at least one electrical stimulation zone; and

defining a program to control delivery of electrical stimulation therapy based on the user input, wherein defining the program comprises;

defining each of a plurality of electrodes, on at least one lead, to deliver at least a portion of the electrical stimulation therapy;

automatically determining an electrical stimulation contribution of each of the plurality of defined electrodes to the at least one stimulation zone; and

automatically determining a stimulation amplitude of the portion of the electrical stimulation therapy delivered by each of the plurality of defined electrodes based on the electrical stimulation contribution of the electrode and the intensity of the at least one electrical stimulation zone, wherein the amplitude of at least one of the plurality of defined electrodes is equal to an amplitude corresponding to the intensity of the at least one electrical stimulation zone, and wherein a sum of the amplitudes of the plurality of defined electrodes is greater than the amplitude corresponding to the intensity of the at least one electrical stimulation zone.

16. The method of claim 15, wherein the user input comprises stretching the representation of the at least one stimulation zone.

17. The method of claim 15, wherein the user input further comprises moving the representation of the at least one stimulation zone from a first location on a display to a second location on the display.

18. The method of claim 15, further comprising:

receiving, via the programmer device, user input that defines the intensity of the at least one electrical stimulation zone.

19. The method of claim 15, further comprising:

controlling at least one of a rate of change of a stretch of the at least one stimulation zone and a rate of change of a move of the at least one stimulation zone.

20. The method of claim 15, further comprising:

generating an electrical stimulation amplitude to be delivered by an electrode carried by a housing of the electrical stimulator based on a sum of the electrical stimulation amplitudes of each of the plurality of defined electrodes.

21. The method of claim 20, further comprising:

modifying, the electrical stimulation amplitude to be delivered by the electrode carried by the housing of the implantable electrical stimulator in response to at least one of the user interface receiving user input graphically defining a representation of another electrical stimulation zone, the at least one electrical stimulation zone moving, and the at least one electrical stimulation zone stretching.

22. The method of claim 15, further comprising:

comparing the determined electrical stimulation contribution of each of the plurality of defined electrodes to a threshold value; and

determining each of the plurality of defined electrodes will be used to deliver at least a portion of the electrical stimulation therapy based on the comparison.

23. The method of claim 15, further comprising:

generating and displaying to a user an indication of zone extent based upon the at least one of the defined electrodes.

24. The method of claim 23, wherein the indication of zone extent displayed to the user provides a visual indication of a relative electrical stimulation contribution of the at least one defined electrode to the at least one stimulation zone.

25. The method of claim 15, further comprising:

receiving, in the programmer device, at least one of user input that moves the representation of the at least one electrical stimulation zone and user input that stretches the representation of the at least one electrical stimulation zone.

26. The method of claim 15, wherein the at least two of the plurality of defined electrodes are the same polarity.

27. The method of claim 15, wherein the program further comprises multiplying the electrical stimulation contribution by the amplitude corresponding to the intensity of the at least one electrical stimulation zone to determine the stimulation amplitude of each of the plurality of defined electrodes within the at least one stimulation zone, wherein the electrode stimulation contribution of at least one of the plurality of defined electrodes is 1.0, and wherein the electrode contribution of a second of the plurality of defined electrodes is less than 1.0.

28. The method of claim 15, further comprising controlling an implantable medical device to deliver stimulation with the plurality of defined electrodes based on the defined stimulation amplitudes.

29. A programmer device for an electrical stimulator, the programmer device comprising:

means for receiving, via the programmer device for the electrical stimulator, user input that graphically manipulates at least one of a size and a shape of a graphical representation of at least one electrical stimulation zone displayed on the programmer device;

means for defining an intensity of the at least one electrical stimulation zone; and

means for defining a program to control delivery of electrical stimulation therapy based on the user input, wherein the means for defining the program comprises;

means for defining, each of a plurality of electrodes, on at least one lead, to deliver at least a portion of the electrical stimulation therapy;

means for automatically determining, an electrical stimulation contribution of each of the plurality of defined electrodes to the at least one stimulation zone; and

means for automatically determining a stimulation amplitude of the portion of the electrical stimulation therapy delivered by each of the plurality of defined electrodes based on the electrical stimulation contribution of the electrode and the intensity of the at least one electrical stimulation zone, wherein the amplitude of at least one of the plurality of defined electrodes is equal to an amplitude corresponding to the intensity of the at least one electrical stimulation zone, and wherein a sum of the amplitudes of the plurality of defined electrodes is greater than the amplitude corresponding to the intensity of the at least one electrical stimulation zone.

30. The programmer device of claim 29, wherein the user input comprises stretching the representation of the at least one stimulation zone.

31. The programmer device of claim 29, wherein the user input further comprises moving the representation of the at least one stimulation zone from a first location on a display to a second location on the display.

32. The programmer device of claim 29, further comprising:

means for receiving, via the programmer device, user input that defines the intensity of the at least one electrical stimulation zone.

33. The programmer device of claim 29, further comprising:

means for controlling at least one of a rate of change of a stretch of the at least one stimulation zone and a rate of change of a move of the at least one stimulation zone.

34. The programmer device of claim 29, further comprising:

means for generating, an electrical stimulation amplitude to be delivered by an electrode carried by a housing of the electrical stimulator based on the electrical stimulation amplitude generated by each of the plurality of defined electrodes.

35. The programmer device of claim 34, further comprising:

means for modifying, the electrical stimulation amplitude to be delivered by the electrode carried by the housing of the electrical stimulator in response to at least one of the user interface receiving user input graphically defining a representation of another electrical stimulation zone, the at least one electrical stimulation zone moving, and the at least one electrical stimulation zone stretching.

36. The programmer device of claim 29, further comprising:

means for comparing the determined electrical stimulation contribution each of the plurality of defined electrodes to a threshold value; and

means for determining each of the plurality of defined electrodes will be used to deliver at least a portion of the electrical stimulation therapy based on the comparison.

37. The programmer device of claim 29, further comprising:

means for generating and displaying to a user an indication of zone extent based upon at least one of the defined electrodes.

38. The programmer device of claim 37, wherein the indication of zone extent displayed to the user provides a visual indication of a relative electrical stimulation contribution of the at least one of the defined electrodes to the at least one stimulation zone.

39. The programmer device of claim 29, wherein the user input comprises at least one of the user interface receiving user input moving the representation of the at least one electrical stimulation zone, and the user interface receiving user input stretching the representation of the at least one electrical stimulation zone.

40. The programming device of claim 29, further comprising means for multiplying the electrical stimulation contribution by the amplitude corresponding to the intensity of the at least one electrical stimulation zone to determine the stimulation amplitude of each of the plurality of defined electrodes within the at least one stimulation zone, wherein the electrode stimulation contribution of at least one of the plurality of defined electrodes is 1.0, and wherein the electrode contribution of a second of the plurality of defined electrodes is greater than 0.0 and less than 1.0.

41. The programming device of claim 29, further comprising

means for controlling an implantable medical device to deliver stimulation with the plurality of defined electrodes based on the defined stimulation amplitudes.

42. A non-transitory computer-readable medium comprising instructions that, upon execution, cause a processor in a programmer for an electrical stimulator to:

receive user input graphically manipulating at least one of a size and a shape of a graphical representation of the at least one electrical stimulation zone displayed on the programmer;

define an intensity of the at least one electrical stimulation zone; and

define a program to control delivery of electrical stimulation therapy based on the user input, wherein the instructions that cause the processor to define the program comprise instructions that cause the processor to;

define each of a plurality of electrodes, on at least one lead, to deliver at least a portion of the electrical stimulation therapy;

automatically determine an electrical stimulation contribution of each of the plurality of defined electrodes to the at least one stimulation zone; and

automatically determine a stimulation amplitude of the portion of the electrical stimulation therapy delivered by each of the plurality of defined electrodes based on the electrical stimulation contribution of the electrode and the intensity of the at least one electrical stimulation zone, wherein the amplitude of at least one of the plurality of defined electrodes is equal to an amplitude corresponding to the intensity of the at least one electrical stimulation zone, and wherein a sum of the amplitudes of the plurality of defined electrodes is greater than the amplitude corresponding to the intensity of the at least one electrical stimulation zone.

43. The computer-readable medium of claim 42, wherein the user input comprises stretching the representation of the at least one defined stimulation zone.

44. The computer-readable medium of claim 42, wherein the user input further comprises moving the representation of the at least one stimulation zone from a first location on a display to a second location on the display.

45. The computer-readable medium of claim 42, further comprising instructions that, upon execution, cause the processor to:

receive user input that defines the intensity of the at least one electrical stimulation zone.

46. The computer-readable medium of claim 42, further comprising instructions that, upon execution, cause the processor to:

control at least one of a rate of change of a stretch of the at least one stimulation zone and a rate of change of a move of the at least one stimulation zone.

47. The computer-readable medium of claim 42, further comprising instructions that, upon execution, cause the processor to:

generate an electrical stimulation amplitude to be delivered by an electrode carried by a housing of an implantable medical device (IMD) based on a sum of the electrical stimulation amplitudes generated each of the plurality of defined electrodes.

48. The computer-readable medium of claim 47, further comprising instructions that, upon execution, cause the processor to:

modify, the electrical stimulation amplitude to be delivered by the electrode carried by the housing of the IMD in response to at least one of the user interface receiving user input graphically defining a representation of another electrical stimulation zone, the at least one electrical stimulation zone moving, and the at least one electrical stimulation zone stretching.

49. The computer-readable medium of claim 42, further comprising instructions that, upon execution, cause the processor to:

receive at least one of user input that moves the representation of the at least one electrical stimulation zone and user input that stretches the representation of the at least one electrical stimulation zone.

50. The computer readable medium of claim 42, further comprising instructions that, upon execution, cause the processor to

multiply the electrical stimulation contribution by the amplitude corresponding to the intensity of the at least one electrical stimulation zone to determine the stimulation amplitude of each of the plurality of defined electrodes within the at least one stimulation zone, wherein the electrode stimulation contribution of at least one of the plurality of defined electrodes is 1.0, and wherein the electrode contribution of a second of the plurality of defined electrodes greater than 0.0 and less than 1.0.

51. The computer readable medium of claim 42, further comprising instructions that, upon execution, cause the processor to

control an implantable medical device to deliver stimulation with the plurality of defined electrodes based on the defined stimulation amplitudes.

52. A system comprising:

an implantable medical device (IMD) configured to deliver electrical stimulation therapy to a patient;

a user interface that displays a graphical representation of at least one electrical stimulation zone and receives user input graphically manipulating at least one of a size and a shape of the representation of the at least one electrical stimulation zone; and

a processor configured to define a program to control delivery of electrical stimulation therapy by a stimulator based on the user input, wherein the processor is further configured to;

define an intensity of the at least one electrical stimulation zone

define each of a plurality of electrodes, on at least one lead, to deliver at least a portion of the electrical stimulation therapy;

automatically determine an electrical stimulation contribution of each of the plurality of defined electrodes to the at least one stimulation zone; and

automatically determine a stimulation amplitude of the portion of the electrical stimulation therapy delivered by each of the plurality of defined electrodes based on the electrical stimulation contribution of the electrode and the intensity of the at least one electrical stimulation zone, wherein the amplitude of at least one of the plurality of defined electrodes is equal to an amplitude corresponding to the intensity of the at least one electrical stimulation zone, and wherein a sum of the amplitudes of the plurality of defined electrodes is greater than the amplitude corresponding to the intensity of the at least one electrical stimulation zone.

53. The system of claim 52, further comprising a programmer device for programming the IMD that includes the user interface and the processor.

54. The system of claim 52, wherein the user input comprises at least one of stretching the representation of the at least one stimulation zone and moving the representation of the at least one stimulation zone from a first location on a display to a second location on the display.

55. The system of claim 52, wherein the user interface further receives user input that defines the intensity of the at least one electrical stimulation zone.

56. The system of claim 52, wherein the processor is configured to control at least one of a rate of change of a stretch of the at least one stimulation zone and a rate of change of a move of the at least one stimulation zone.

57. The system of claim 52, wherein the processor is further configured to:

generate, an electrical stimulation amplitude to be delivered by an electrode carried by a housing of the IMD based on the electrical stimulation amplitude generated by each of the plurality of defined electrodes.

58. The system of claim 57, wherein the processor is further configured to:

modify, the electrical stimulation amplitude to be delivered by the electrode carried by the housing of the IMD in response to at least one of the user interface receiving user input graphically defining a representation of another electrical stimulation zone, the at least one electrical stimulation zone moving, and the at least one electrical stimulation zone stretching.

59. The system of claim 57, wherein the processor is further configured to:

compare the determined electrical stimulation contribution of each of the plurality of defined electrodes to a threshold value; and

determine whether each of the plurality of defined electrodes will be used to deliver at least a portion of the electrical stimulation therapy based on the comparison.

60. The system of claim 57, wherein the processor is further configured to:

generate and display to a user an indication of zone extent based upon at least one of the defined electrodes.

61. The system of claim 60, wherein the indication of zone extent displayed to the user provides a visual indication of a relative electrical stimulation contribution of the at least one of the defined electrodes to the at least one stimulation zone.

62. The system of claim 52, wherein the processor is further configured to

multiply the electrical stimulation contribution by the amplitude corresponding to the intensity of the at least one electrical stimulation zone to determine the stimulation amplitude of each of the plurality of defined electrodes within the at least one stimulation zone, wherein the electrode stimulation contribution of at least one of the plurality of defined electrodes is 1.0, and wherein the electrode contribution of a second of the plurality of defined electrodes is greater than 0.0 and less than 1.0.

63. The system of claim 52, wherein the processor is further configured to

control the IMD to deliver stimulation with the plurality of defined electrodes based on the defined stimulation amplitudes.