Transcatheter heart valves

• US 8,998,979 B2
• Filed: 02/11/2014
• Issued: 04/07/2015
• Est. Priority Date: 11/17/1999
• Status: Expired due to Fees

• Current Assignee: Medtronic Corevalve LLC (Medtronic Plc)
• Original Assignee: Medtronic Corevalve LLC (Medtronic Plc)
• Inventors: Seguin, Jacques, Bortlein, Georg
• Primary Examiner(s): Isabella, David
• Assistant Examiner(s): SCHILLINGER, ANN M
• Application Number:
  US14/177,806
• Publication Number:
  US 20140194978A1
• Time in Patent Office: 420 Days
• US Class Current: 623/2.1
• CPC Class Codes: A61B 17/0218 for minimally invasive surgery A61B17/0281, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2/2409 Support rings therefor, e.g. for connecting valves to tissue annuloplasty rings A61F2/2442
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2427 Devices for manipulating or deploying heart valves during implantation
• CPC Class Codes: A61F 2/2433 using balloon catheter
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2/93 circumferentially expandable by using ratcheting locks
• CPC Class Codes: A61F 2002/91558 connected peak to peak
• CPC Class Codes: A61F 2002/91591 Locking connectors, e.g. using male-female connections
• CPC Class Codes: A61F 2210/0023 operated at different temperatures whilst inside or touching the human body, heated or cooled by external energy source or cold supply
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2220/0058 soldered or brazed or welded
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0067 : conical
• CPC Class Codes: A61F 2230/0078 : hyperboloidal
• CPC Class Codes: A61F 2250/0003 : having an inflatable pocket filled with fluid, e.g. liquid or gas
• CPC Class Codes: A61F 2250/0039 : differing in diameter
• CPC Class Codes: A61F 2250/0048 : differing in mechanical expandability, e.g. in mechanical, self- or balloon expandability
• CPC Class Codes: A61F 2250/0069 : Sealing means

Abstract

A prosthetic heart valve comprises a biological tissue valve and a collapsible and expandable support frame comprising a longitudinal axis. The frame comprises an outflow circumferential structure defining an outflow end of the frame and defining a similar row of expandable cells, and a circumferential undulating strut structure spaced apart from the outflow circumferential structure. The frame also comprises three struts longitudinally aligned with the longitudinal axis, configured to facilitate mounting the biological tissue valve to the frame, and interconnecting the outflow circumferential structure to the circumferential undulating structure. Each strut comprises a first end terminating at a respective junction between two adjacent expandable cells of the outflow circumferential structure, and a second end terminating at the circumferential undulating strut structure. The prosthetic heart valve is configured to be collapsed for introduction into a patient using a catheter and to be expanded for deployment at an implantation site.

Claims

1. A prosthetic heart valve comprising:

a biological tissue valve; and

a collapsible and expandable support frame comprising a longitudinal axis, the frame comprising;

an outflow circumferential structure defining an outflow end of the frame and defining a single row of expandable cells, wherein each cell defines a separate side opening of the outflow circumferential structure;

a circumferential undulating strut structure spaced apart from the outflow circumferential structure; and

three struts longitudinally aligned with the longitudinal axis of the frame, configured to facilitate mounting the biological tissue valve to the frame, and interconnecting the outflow circumferential structure to the circumferential undulating structure, each strut of the three struts comprising;

a first end terminating at a respective junction between two adjacent expandable cells of the outflow circumferential structure; and

a second end terminating at the circumferential undulating strut structure,

wherein the prosthetic heart valve is configured to be collapsed for introduction into a patient using a catheter and to be expanded for deployment at an implantation site.

2. The prosthetic heart valve of claim 1, wherein the expandable cells are diamond shaped.

3. The prosthetic heart valve of claim 1, wherein the frame is configured to be balloon expandable.

4. The prosthetic heart valve of claim 1, wherein the frame comprises a shape memory material.

5. The prosthetic heart valve of claim 4, wherein the shape memory material comprises a nickel-titanium alloy.

6. The prosthetic heart valve of claim 1, wherein a portion of the prosthetic heart valve is configured to be positioned at a native cardiac ring upon implantation.

7. The prosthetic heart valve of claim 1, wherein the biological tissue valve is connected to the frame using sutures.

8. The prosthetic heart valve of claim 1, wherein the frame is tubular.

9. The prosthetic heart valve of claim 1, further comprising a sealing layer connected to the frame and configured to seal the prosthetic heart valve.

10. A prosthetic heart valve comprising:

a biological tissue valve;

a collapsible and expandable support frame comprising a longitudinal axis, the frame comprising;

an outflow circumferential structure defining an outflow end of the frame and consisting essentially of a single row of expandable cells, wherein each cell defines a separate side opening of the outflow circumferential structure;

three struts longitudinally aligned with the longitudinal axis of the frame and configured to facilitate mounting the biological tissue valve to the frame, each strut of the three struts comprising a first end joined to a respective junction between two adjacent expandable cells of the outflow circumferential structure and a second end; and

a circumferential undulating strut structure spaced apart from the outflow circumferential structure, and comprising a plurality of peaks each joined to a respective second end of one strut of the three struts,

wherein the prosthetic heart valve is configured to be collapsed for introduction into a patient using a catheter and to be expanded for deployment at an implantation site.

11. The prosthetic heart valve of claim 10, wherein the expandable cells are diamond shaped.

12. The prosthetic heart valve of claim 10, wherein the frame is configured to be balloon expandable.

13. The prosthetic heart valve of claim 10, wherein the frame comprises a shape memory material.

14. The prosthetic heart valve of claim 13, wherein the shape memory material comprises a nickel-titanium alloy.

15. The prosthetic heart valve of claim 10, wherein a portion of the prosthetic heart valve is configured to be positioned at a native cardiac ring upon deployment.

16. The prosthetic heart valve of claim 10, wherein the biological tissue valve is joined to the frame using sutures.

17. The prosthetic heart valve of claim 10, wherein the frame is tubular.

18. The prosthetic heart valve of claim 10, further comprising a sealing layer joined to the frame and configured to conform to any surface irregularities at or near an existing cardiac ring.