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Implantable article, method of forming same and method for reducing thrombogenicity

  • US 8,999,364 B2
  • Filed: 05/25/2007
  • Issued: 04/07/2015
  • Est. Priority Date: 06/15/2004
  • Status: Active Grant
First Claim
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1. An implantable device comprising:

  • a central core defining a lumen through said core with an inner core surface along said lumen and an outer core surface;

    at least one first degradable layer formed upon said inner core surface and said outer core surface for contacting bodily fluid or tissue, wherein the first degradable layer comprises a polymer selected from the group consisting of PLGA 80/20, PLGA 75/25, and PLGA 53/47; and

    at least one second degradable layer formed between said inner core surface and said first degradable layer and also between said outer core surface and said first degradable layer, wherein said first degradable layer has a first degradation rate and said second degradable layer has a second degradation rate such that said at least one first degradable layer degrades more rapidly than said at least one second degradable layer on contact with bodily fluid or tissue.

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