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Functionalized membrane for a chamber for encapsulating cells producing at least one substance of therapeutic interest and bioartificial organ comprising such a membrane

  • US 9,005,960 B2
  • Filed: 05/31/2011
  • Issued: 04/14/2015
  • Est. Priority Date: 06/04/2010
  • Status: Expired due to Fees
First Claim
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1. A functionalized semi-permeable membrane for production of a chamber for encapsulating secretory cells of a bioartificial organ composed of a porous biocompatible support, wherein:

  • said porous biocompatible support is pretreated so that its surface energy is greater than or equal to 50 mJ·

    m

    2
    ;

    pores of said porous biocompatible support have an inner size between 5 and 100 nm, andsaid functionalized semi-permeable membrane comprises at least two layers each comprising a hydrophilic polymer and at least one biologically active molecule.

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