Please download the dossier by clicking on the dossier button x
×

Optical reporter compositions

  • US 9,005,985 B2
  • Filed: 02/07/2013
  • Issued: 04/14/2015
  • Est. Priority Date: 04/16/2003
  • Status: Active Grant
First Claim
Patent Images

1. A composition of the formula I:


  • (cOpR)-[L-(NA)]m



    Iwherein;

    m is an integer greater than 1;

    (cOpR) is a coated optical reporter particle, wherein the cOpR comprises an upconverting phosphor (UCP) material of the formula Na(YxYbyErz)F4, and wherein;

    x is from about 0.6 to about 0.95;

    y is from about 0.05 to about 0.35; and

    z is from about 0.1 to about 0.001;

    (NA) is a nucleic acid oligomer of detectable sequence; and

    L is a linking group covalently bound to the coated optical reporter particle and to the nucleic acid oligomer;

    provided that at least one of the following applies;

    x is not from 0.7 to 0.9; and

    /ory is not from 0.08 to 0.29; and

    /orz is not from 0.01 to 0.06.

View all claims
  • 3 Assignments
Timeline View
Assignment View
    ×
    ×