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Heterotrifunctional molecules and methods for the synthesis of dendrimeric materials

  • US 9,006,345 B2
  • Filed: 03/26/2012
  • Issued: 04/14/2015
  • Est. Priority Date: 03/25/2011
  • Status: Expired due to Fees
First Claim
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1. A method for generating a dendrimer comprising a heterobifunctional core, a heterobifunctional macromolecule, and a heterotrifunctional branch, the method comprising:

  • (a) covalently linking a heterobifunctional core comprised of an α

    -substituted click moiety group and an ω

    -substituted click moiety group with a first heterobifunctional macromolecule or a first heterotrifunctional branch, wherein said heterobifunctional macromolecule or heterotrifunctional branch is comprised of a first click moiety group and a first terminus wherein the first terminus is comprised of a second click moiety group or a non-click functional group, and(b) covalently linking the heterobifunctional macromolecule or heterotrifunctional branch with a second heterobifunctional macromolecule or heterotrifunctional branch.

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