×

On-body microsensor for biomonitoring

  • US 9,008,745 B2
  • Filed: 03/14/2014
  • Issued: 04/14/2015
  • Est. Priority Date: 03/14/2013
  • Status: Active Grant
First Claim
Patent Images

1. A sensor for sensing analytes present in a body fluid of a user, the sensor comprising:

  • a substrate composed of a semiconducting material; and

    a filament including;

    a substrate core defined at the substrate, the substrate core including a base end coupled to the substrate, a columnar protrusion having a proximal portion coupled to the base end and a distal portion, and a tip region coupled to the distal portion of the columnar protrusion and that facilitates access to the body fluid of the user;

    a conductive layer, isolated to the tip region of the substrate core and isolated away from the base end and the columnar protrusion as an active region that enables transmission of electronic signals generated upon detection of an analyte;

    an insulating layer ensheathing the columnar protrusion and base end of the substrate core and exposing a portion of the conductive layer, thereby defining a boundary of the active region;

    a sensing layer, in communication with the active region, characterized by reversible redox behavior for transduction of an ionic concentration of the analyte into an electronic signal;

    an intermediate selective layer superficial to the conductive layer and deeper than the sensing layer, relative to a most distal point of the tip region of the filament, that facilitates detection of the analyte;

    an intermediate protective layer, superficial to the intermediate selective layer, including a functional compound that promotes generation of a protective barrier; and

    a selective coating superficial to the intermediate protective layer, having a distribution of molecules that respond to presence of the analyte, superficial to the sensing layer.

View all claims
  • 2 Assignments
Timeline View
Assignment View
    ×
    ×