Pen-type injector

• US 9,011,391 B2
• Filed: 06/17/2013
• Issued: 04/21/2015
• Est. Priority Date: 03/03/2003
• Status: Expired due to Term

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Inventors: Veasey, Robert Frederick, Perkins, Robert, Plumptre, David Aubrey
• Primary Examiner(s): MENDEZ, MANUEL A
• Application Number:
  US13/919,251
• Publication Number:
  US 20130304024A1
• Time in Patent Office: 673 Days
• Field of Search: 604/187, 604207-211, 604/218, 604/221, 604/224, 604/232
• US Class Current: 604/209
• CPC Class Codes: A61M 2005/2407 from the rear
• CPC Class Codes: A61M 2005/3126 Specific display means related to dosing
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/31528 by means of rotational movements, e.g. screw-thread mechanisms
• CPC Class Codes: A61M 5/31533 Dosing mechanisms, i.e. setting a dose administrating mechanisms A61M5/31565
• CPC Class Codes: A61M 5/31535 Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
• CPC Class Codes: A61M 5/31536 Blocking means to immobilize a selected dose, e.g. to administer equal doses
• CPC Class Codes: A61M 5/31541 Means preventing setting of a dose beyond the amount remaining in the cartridge
• CPC Class Codes: A61M 5/31546 Electrically operated dose setting, e.g. input via touch screen or plus/minus buttons
• CPC Class Codes: A61M 5/31551 including axial movement of dose setting member
• CPC Class Codes: A61M 5/3156 using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
• CPC Class Codes: A61M 5/31563 interacting with a displaceable stop member
• CPC Class Codes: A61M 5/31565 Administration mechanisms, i.e. constructional features, modes of administering a dose dosing mechanisms for setting a dose A61M5/31533
• CPC Class Codes: A61M 5/31568 Means keeping track of the total dose administered, e.g. since the cartridge was inserted
• CPC Class Codes: A61M 5/3157 Means providing feedback signals when administration is completed A61M5/20 takes precedence
• CPC Class Codes: A61M 5/31575 using scaling up or down transmissions, e.g. gearbox
• CPC Class Codes: A61M 5/31578 based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
• CPC Class Codes: A61M 5/31585 performed by axially moving actuator, e.g. an injection button
• CPC Class Codes: A61M 5/31593 : Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
• CPC Class Codes: A61M 5/32 : Needles; Details of needles pertaining to their connection with syringe or hub infusion needles A61M5/158; Accessories for bringing the needle into, or holding the needle on, the body A61M5/42, A61M5/46 take precedence; guide needles for catheters A61M25/065; Devices for protection of needles apparatus specially adapted for cleaning or sterilising needles A61M5/001

Abstract

The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose-cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same.

Claims

1. A method of determining a final dose of a medicament contained in a cartridge in a pen-type injector comprising,

providing a housing containing a drive sleeve having a nut threadedly engaged to an outer surface of the drive sleeve between a first and second flange;

configuring the nut and thread to be indicative of dispensed doses; and

configuring the second flange to engage the nut when a final dose of medicament is dispensed from a cartridge attached to the pen-type injector,

wherein an inner surface of the housing is configured to engage an outer surface of the nut to prevent rotation of the nut relative to the housing.

2. The method of claim 1 further comprising configuring the nut and second flange to prevent the drive sleeve from rotating when the final dose of medicament is dispensed.

3. The method of claim 1 further comprising configuring the threads to be proportional to all available doses of medicament contained in a cartridge attached to the pen-type injector.

4. The method of claim 1 further comprising configuring the nut to be a half nut and pushing the nut onto threads at a position indicative of a completely filled medicament cartridge.

5. The method of claim 4 further comprising configuring the first flange and the nut each with a radial stop so that the radial stops are engaged indicating a cartridge full position.

6. The method of claim 1 further comprising configuring the nut and second flange with radial stops such that axial travel of the radial stop on the nut engages the radial stop on the second flange when a final dose of medicament is dispensed from a cartridge attached to the pen-type injector.

7. The method of claim 1 further comprising configuring the drive sleeve to rotate relative to the nut causing the nut to move axially along the threads a distance proportional to each dispensed dose.

8. A method of determining a final dose of a medicament contained in a cartridge in a pen-type injector comprising,

rotating a drive sleeve having a threaded outer surface positioned between a first and second flange during setting of a dose of medicament;

axially moving, but not rotating, a nut engaged to the threaded outer surface during rotation of the drive sleeve during dose setting, whereby the axial position of the along the threads is indicative of dispensed doses; and

engaging the nut with the second flange when a final dose of medicament remains in a cartridge attached to the pen-type injector,

wherein an outer surface of the nut engages an inner surface of a housing to prevent rotation of the nut relative to the housing.