Methods and devices for delivering agents across biological barriers
First Claim
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1. A method of manufacturing a device for delivering an agent across a biological barrier comprising:
- providing a first microneedle having a first integrated reservoir which is an opening through the entirety of the width of the first microneedle, wherein the first microneedle extends from a first substrate, wherein a first depth guard extends from the first substrate, and wherein the first microneedle, the first substrate, and the first depth guard are integrally formed as a continuous single unit; and
filling the first integrated reservoir with an agent by selectively depositing a predetermined volume of the agent into the first integrated reservoir utilizing a micropipette or a syringe, such that the agent is contained predominantly within the interior volume of the microneedle.
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Abstract
The invention provides for microneedle devices for delivering agents across biological barriers. The microneedles include agent reservoirs integrated into the bodies of the microneedles, themselves.
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Citations
4 Claims
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1. A method of manufacturing a device for delivering an agent across a biological barrier comprising:
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providing a first microneedle having a first integrated reservoir which is an opening through the entirety of the width of the first microneedle, wherein the first microneedle extends from a first substrate, wherein a first depth guard extends from the first substrate, and wherein the first microneedle, the first substrate, and the first depth guard are integrally formed as a continuous single unit; and filling the first integrated reservoir with an agent by selectively depositing a predetermined volume of the agent into the first integrated reservoir utilizing a micropipette or a syringe, such that the agent is contained predominantly within the interior volume of the microneedle. - View Dependent Claims (2, 3, 4)
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Specification