Lead fault detection for implantable medical device

• US 9,014,807 B2
• Filed: 11/16/2011
• Issued: 04/21/2015
• Est. Priority Date: 12/20/2010
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Bocek, Joseph M., White, Harley G., Gilkerson, James O., Link, John M.
• Primary Examiner(s): Bertram, Eric D.
• Assistant Examiner(s): So, Elizabeth K
• Application Number:
  US13/297,785
• Publication Number:
  US 20120158089A1
• Time in Patent Office: 1,252 Days
• US Class Current: 607/28
• CPC Class Codes: A61B 2560/0276 Determining malfunction
• CPC Class Codes: A61N 1/00 Electrotherapy; Circuits therefor A61N2/00 takes precedence; irradiation apparatus A61N5/00
• CPC Class Codes: A61N 1/36521 the parameter being derived from measurement of an electrical impedance
• CPC Class Codes: A61N 1/37 Monitoring; Protecting

Abstract

An implantable medical device can include a therapy circuit coupled to a therapy delivery terminal, the therapy circuit configured to generate a specified electrostimulation therapy for delivery to a tissue site via the therapy delivery terminal, and a measurement circuit for measuring at least two impedances of a first terminal combination including the therapy delivery terminal, the two impedances corresponding to at least two instances of excitation separated enough in time to capture an impedance artifact due at least in part to a motion of the heart, such as to determine an electrostimulation therapy lead status at least in part using the at least two impedances.

Claims

1. An apparatus, comprising:

an implantable medical device, comprising;

a therapy circuit coupled to a therapy delivery terminal, the therapy circuit configured to generate a specified electrostimulation therapy for delivery to a tissue site via the therapy delivery terminal;

a measurement circuit comprising;

an excitation circuit, configured to generate multiple instances of a non-therapeutic, non-tissue-stimulating voltage or current excitation using a first terminal combination including the therapy delivery terminal, within the duration of a cardiac cycle; and

a detector circuit, configured to receive corresponding voltages or currents developed at the first terminal combination in response to the multiple instances of excitation, within the duration of the cardiac cycle; and

a processor circuit coupled to the measurement circuit and configured to determine at least two impedances using information about the instances of excitation, and information provided by the measurement circuit about the received voltages or currents, the two impedances corresponding to at least two instances of excitation separated enough in time to capture an impedance artifact indicative of a status of an electrostimulation therapy lead, the impedance artifact elicited at least in part by a motion of the heart;

wherein the processor circuit is configured to determine the electrostimulation therapy lead status at least in part using the at least two impedances.

2. The apparatus of claim 1, wherein the excitation circuit is configured to generate a current excitation at the first terminal combination;

and

wherein the detector is configured receive a voltage developed at the first terminal combination in response to the current excitation.

3. The apparatus of claim 2, wherein the excitation circuit is configured to inject a pulsed current excitation into the first terminal combination, the first terminal combination comprising a reference terminal;

and

wherein the detector circuit is configured to measure a voltage developed across the first terminal combination.

4. The apparatus of claim 1, wherein the excitation circuit is configured to generate a voltage excitation across the first terminal combination;

and

wherein the detector circuit is configured to receive a current developed at the first terminal combination in response to the voltage excitation.

5. The apparatus of claim 1, further comprising an implantable lead, including an implantable electrode, the implantable lead providing an electrical coupling between a terminal included in the first terminal combination and the electrode.

6. The apparatus of claim 1, comprising a first comparator configured to compare an impedance determined by the processor circuit against a specified range;

and

in response, wherein the processor circuit is configured to declare an alert if the impedance falls outside the specified range.

7. The apparatus of claim 6, wherein the specified range is determined using information about one or more previously-determined impedances.

8. The apparatus of claim 6, wherein the specified range includes an upper threshold and a lower threshold;

and

wherein one or more of the upper or lower thresholds are adjusted using an adjusted threshold specified relative to a central tendency of previously-determined impedances.

9. The apparatus of claim 6, wherein the specified range is determined using information about the type or location of an implantable lead, the lead including the electrode coupled to the terminal included in the first terminal combination.

10. The apparatus of claim 6, wherein the processor circuit is configured to adjust the interval between successive instances of excitation.

11. The apparatus of claim 10, wherein the processor circuit is configured to decrease the interval between successive instances of excitation in response to a declared alert.

12. The apparatus of claim 6, wherein the processor circuit is configured to count a number of alerts;

and

wherein the apparatus comprises a second comparator configured to compare a count of the number of alerts against a specified threshold; and

in response, wherein the processor circuit is configured to declare a lead fault when the count of the number of alerts exceeds the specified threshold.

13. The apparatus of claim 6, further comprising an external assembly;

and

wherein the implantable medical device comprises a telemetry circuit configured to transfer information, between the implantable medical device and the external assembly, about one or more instances of the measurement circuit excitation, the received voltage or current, the determined impedance, a count of declared alerts, or a lead status indicative of a lead fault.

14. The apparatus of claim 6, wherein the processor circuit is configured to adjust the electrostimulation electrode configuration or one or more electrostimulation parameters to be used by the therapy circuit for providing subsequent electrostimulation, in response to information about the alert.

15. The apparatus of claim 6, wherein the processor circuit is configured to select a second terminal combination for use in providing subsequent electrostimulation in response to an alert declared in relation to an impedance determine at least in part using the first terminal combination.

16. The apparatus of claim 1, wherein the processor circuit is configured to determine a relative indication of information between at least two impedances corresponding to at least two excitation instances provided by the measurement circuit within an interval of a single cardiac cycle;

wherein the apparatus includes a comparator configured to compare the relative indication of information to a threshold; and

wherein the processor circuit is configure to declare an alert, in response, if the relative indication of information exceeds the threshold.