Neurostimulation system for matching ideal pole spacing with effective electrode separation

• US 9,014,820 B2
• Filed: 03/14/2012
• Issued: 04/21/2015
• Est. Priority Date: 03/15/2011
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Lee, Dongchul, Zhu, Changfang
• Primary Examiner(s): Koharski, Christopher D
• Assistant Examiner(s): D ABREU, MICHAEL JOSEPH
• Application Number:
  US13/420,312
• Publication Number:
  US 20120239116A1
• Time in Patent Office: 1,133 Days
• Field of Search: 607/62, 607/116
• US Class Current: 607/117
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/36185 Selection of the electrode configuration
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means
• CPC Class Codes: G16H 20/30 relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
• CPC Class Codes: G16H 40/40 for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
• CPC Class Codes: G16H 40/63 for local operation

Abstract

A system for a neurostimulator coupled to electrodes. The system comprises a input device configured for generating control signals, and control circuitry configured for defining at least one ideal multipole configuration relative to the electrodes in response to the control signals, the control circuitry, for each of the ideal multipole configuration(s), being further configured for, designating at least one of the electrodes as a reference electrode, estimating an effective electrode separation at each of the reference electrode(s), defining a spacing between the poles based on the estimated effective electrode separation at each of the reference electrode(s), generating at least one stimulation parameter set respectively corresponding to the ideal multipole configuration(s), each of the stimulation parameter set(s) defining relative amplitude values for the electrodes that emulate the respective ideal multipole configuration, and instructing the electrical neurostimulator to convey electrical energy to the electrodes in accordance with the stimulation parameter set(s).

Claims

1. A system for an electrical neurostimulator coupled to a plurality of electrodes, comprising:

a user-controlled input device configured for generating control signals; and

control circuitry configured for defining at least one ideal multipole configuration relative to the plurality of electrodes in response to the control signals, each of the at least one ideal multipole configuration having at least two poles aligned along a pole axis, the control circuitry, for each of the at least one ideal multipole configuration, being further configured for, designating at least one of the electrodes as a reference electrode, estimating an effective electrode separation at each of the at least one reference electrode, defining a spacing between the at least two poles based on the estimated effective electrode separation at each of the at least one reference electrode, generating at least one stimulation parameter set respectively corresponding to the at least one ideal multipole configuration, each of the at least one stimulation parameter set defining relative amplitude values for the plurality of electrodes that emulate the respective ideal multipole configuration, and instructing the electrical neurostimulator to convey electrical energy to the plurality of electrodes in accordance with the at least one stimulation parameter set.

2. The system of claim 1, wherein the control circuitry is configured for estimating an effective electrode separation at a point in space along the pole axis based on the estimated effective electrode separation at each of the at least one reference electrode, and defining the spacing between the at least two poles based on the estimated effective electrode separation at the point in space along the pole axis.

3. The system of claim 2, wherein the control circuitry is configured for defining the spacing between the at least two poles to be a multiple of the estimated effective electrode separation at the point in space along the pole axis.

4. The system of claim 3, wherein the at least one reference electrode comprises a plurality of reference electrodes, and the control circuitry is configured for estimating an effective electrode separation at a point in space along the pole axis by computing a weighted average of the estimated effective electrode separations at the plurality of reference electrodes.

5. The system of claim 4, wherein the estimated effective electrode separations at the plurality of reference electrodes are weighted based on a distance between the point in space and the reference electrodes.

6. The system of claim 5, wherein each of the distances between the point in space and the reference electrodes has a first directional component perpendicular to the pole axis and a second directional component parallel to the pole axis, and wherein the control circuitry is configured for estimating the effective electrode separation at the point in space along the pole axis in accordance with the equation:

7. The system of claim 6, wherein W_x(j)=e⁽⁻

|x−

E<sup>x(j)|·

λ

x)</sup> and W_y=e<sup>(−

|y−

Ey(j)|·

λ

y)</sup>, where λ

_x and λ

_y are constants, x is the coordinate of the point in space along an axis perpendicular to the pole axis, y is the coordinate of the point in space along the pole axis, E_x is the coordinate of the position of the reference electrode j along an axis perpendicular to the pole axis, and E_y is the coordinate of the position of the reference electrode j along the pole axis.

8. The system of claim 7, wherein λ

_x is greater than λ

_y.

9. The system of claim 3, wherein the control circuitry is configured for estimating an effective electrode separation at a point in space along the pole axis by computing a weighted average of the estimated effective electrode separations at the plurality of reference electrodes and maximum electrode separations at a plurality of imaginary electrodes surrounding the plurality of reference electrodes.

10. The system of claim 9, wherein the plurality of imaginary electrodes comprises two imaginary electrodes for each of the reference electrodes respectively located on two lines that are parallel to the pole axis.

11. The system of claim 3, wherein the control circuitry is configured for determining the spacing between the two poles to be equal to the estimated effective electrode separation at the point in space along the pole axis.

12. The system of claim 1, wherein the control circuitry is configured for estimating the effective electrode separation at each of the at least one reference electrode by computing a weighted average of actual separations between the respective reference electrode and indexed ones of the electrodes.

13. The system of claim 12, wherein the control circuitry is configured for only selecting as the indexed electrodes, the electrodes located on one side of a line intersecting the respective reference electrode.

14. The system of claim 13, wherein the line is perpendicular to the pole axis.

15. The system of claim 14, wherein the effective electrode separation at any of the at least one reference electrode is estimated to be a maximum value if at least one of the following conditions is satisfied:

no electrodes are located on the one side of the line intersecting the respective reference electrode or the actual separations between the respective reference electrode and all electrodes located on the one side of the line intersecting the respective reference electrode are below a minimum value.

16. The system of claim 12, wherein each of the actual separations between the respective reference electrode and the indexed electrodes has a first directional component perpendicular to the pole axis and a second directional component parallel to the pole axis, and wherein the control circuitry is configured for estimating the effective electrode separation at each of the at least one reference electrode in

accordance with the equation:

17. The system of claim 16, wherein W_x(i)=e⁽⁻

d<sup>x(i)·

λ

x)</sup> and W_y(i)=e<sup>(−

dy(i)·

λ

y)</sup>, where λ

_x and λ

_y are constants, and d_x is the first directional component of the actual separation between the reference electrode and the indexed electrode i.

18. The system of claim 17, wherein λ

_x is greater than λ

_y.

19. The system of claim 1, wherein the at least one ideal multiple configuration comprises a plurality of ideal multipole configurations.

20. The system of claim 19, wherein the control signals are directional control signals.

21. The system of claim 20, wherein the user-controlled input device comprises one or more of a graphical arrow, a joystick, a touchpad, a button pad, a group of keyboard arrow keys, a mouse, a roller ball tracking device, and horizontal and vertical rocker-type arm switches for generating the directional control signals.

22. The system of claim 1, wherein the ideal multipole configuration is one of an ideal bipole configuration and an ideal tripole configuration.

23. The system of claim 1, wherein the two poles have different polarities.

24. The system of claim 1, wherein the plurality of electrodes have non-uniform spacings.

25. The system of claim 1, further comprising telemetry circuitry, wherein the control circuitry is configured for transmitting the at least one stimulation parameter set to the neurostimulation device via the telemetry circuitry.

26. The system of claim 1, further comprising a housing containing the user input device and the control circuitry.