Occlusion perfusion catheter

• US 9,017,285 B2
• Filed: 02/08/2013
• Issued: 04/28/2015
• Est. Priority Date: 11/03/2008
• Status: Active Grant

• Current Assignee: Advanced Catheter Therapies, Inc.
• Original Assignee: Advanced Catheter Therapies, Inc.
• Inventors: Teeslink, C. Rex, Hoyns, Dirk V.
• Primary Examiner(s): BOUCHELLE, LAURA A
• Application Number:
  US13/763,592
• Publication Number:
  US 20140051997A1
• Time in Patent Office: 809 Days
• Field of Search: 604/96.01, 604/99.01, 604/99.02, 604/101.01, 604/101.03, 604/101.05, 604/101.06, 604/102.02, 604/507, 604/508, 604/509
• US Class Current: 604/101.01
• CPC Class Codes: A61B 1/043 for fluorescence imaging
• CPC Class Codes: A61B 17/12045 double occlusion, e.g. during anastomosis
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 2017/00893 pharmaceutically effective
• CPC Class Codes: A61B 2017/12127 Double occlusion, e.g. for creating blood-free anastomosis site
• CPC Class Codes: A61B 5/02154 by optical transmission
• CPC Class Codes: A61B 5/02158 provided with two or more sensor elements
• CPC Class Codes: A61B 5/6853 with a balloon
• CPC Class Codes: A61M 1/90 Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
• CPC Class Codes: A61M 2025/0183 Rapid exchange or monorail catheters
• CPC Class Codes: A61M 2025/1013 with concentrically mounted balloons, e.g. being independently inflatable
• CPC Class Codes: A61M 2025/105 having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 2025/1079 having radio-opaque markers in the region of the balloon
• CPC Class Codes: A61M 2025/1093 having particular tip characteristics
• CPC Class Codes: A61M 2025/1097 with perfusion means for enabling blood circulation only while the balloon is in an inflated state, e.g. temporary by-pass within balloon
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/3337 Controlling, regulating pressure or flow by means of a valve by-passing a pump
• CPC Class Codes: A61M 2205/3344 Measuring or controlling pressure at the body treatment site
• CPC Class Codes: A61M 25/1011 : Multiple balloon catheters
• CPC Class Codes: A61M 39/24 : Check- or non-return valves
• CPC Class Codes: A61M 5/007 : for contrast media

Abstract

Catheters for occluding, visualizing, irrigating, evacuating, and delivering agents to a treatment area are disclosed. The catheters comprise a catheter body comprising five lumens, first and second occlusion balloons coupled to the catheter body, an optional space-occupying balloon coupled to the catheter body and disposed between the first and second occlusion balloons, and an optional visualization means that enables visualization between the first and second occlusion balloons. Methods for using these catheters are also disclosed. A method comprises inflating the first and second occlusion balloons, inflating the space-occupying balloon, allowing fluid to exit via an evacuation lumen, optionally irrigating or aspirating to facilitate fluid exit via said lumen, and delivering an agent to a treatment area via the agent lumen.

Claims

1. A method of visualizing a lumen comprising:

a) inserting a catheter into the lumen, said catheter comprising a longitudinal axis;

b) isolating a treatment region within the lumen;

c) optionally evacuating the isolated treatment region;

d) optionally flushing the isolated treatment region; and

e) introducing a visualization means into the isolated treatment region, via said catheter, wherein said visualization means may turn about the longitudinal axis via torque applied to said visualization means, and wherein said visualization means may activate a photoreactive agent

wherein said catheter comprises an agent delivery lumen, and said agent delivery lumen comprising a delivery skive port, and said introducing comprises;

i) selecting a pressure to be detected within the delivery skive port or within the agent delivery lumen; and

ii) detecting said pressure.

2. The method of claim 1, further comprising introducing, via said catheter, a photoreactive agent into the isolated treatment region.

3. The method of claim 2, wherein:

a) said catheter further comprises;

i) a catheter shaft having a proximal end, and a distal end having a shaft distal tip;

ii) a first balloon positioned on the shaft proximal to the shaft distal tip;

iii) a second balloon positioned on the shaft proximal to the first balloon;

iv) an agent delivery segment positioned on the shaft between the first and second balloons, having one agent delivery segment orifice formed therein, and an agent delivery lumen in fluid communication with said agent delivery segment orifice;

v) an aspiration segment positioned on the shaft between the first and second balloons and having one aspiration segment orifice formed therein;

vi) wherein said visualization means enables visualization of the lumen between the first and second balloons;

vii) a guidewire lumen formed within the shaft and in communication with;

an opening formed in the proximal end of the catheter; and

an opening formed in the shaft distal tip; and

b) said isolating further comprises inflating the first and second balloons.

4. The method of claim 3, wherein said catheter further comprises a visualization means lumen in communication with a visualization means slot, and wherein said visualization means extends through said visualization means lumen at least to said visualization means slot.

5. The method of claim 1, further comprising flushing the isolated treatment region.

6. The method of claim 1, further comprising evacuating the isolated treatment region.

7. The method of claim 1, further comprising evacuating the treatment region and flushing the treatment region.

8. A method of introducing at least one agent into the media of a vessel wall, comprising:

a) inserting a catheter into the lumen, said catheter comprising a longitudinal axis;

b) isolating a treatment region within the lumen;

c) optionally evacuating the isolated treatment region;

d) optionally flushing the isolated treatment region; and

e) introducing a visualization means into the isolated treatment region, via said catheter, wherein said visualization means may turn about the longitudinal axis via torque applied to said visualization means, and wherein said visualization means may activate a photoreactive agent,

wherein said catheter comprises an agent delivery lumen, and said agent delivery lumen comprising a delivery skive port, and said introducing comprises;

i) selecting a pressure to be detected within the delivery skive port or within the agent delivery lumen; and

ii) detecting said pressure.

9. The method of claim 8, further comprising introducing, via said catheter, a photoreactive agent into the isolated treatment region.

10. The method of claim 9, wherein:

a) said catheter further comprises;

i) a catheter shaft having a proximal end, and a distal end having a shaft distal tip;

ii) a first balloon positioned on the shaft proximal to the shaft distal tip;

iii) a second balloon positioned on the shaft proximal to the first balloon;

iv) an agent delivery segment positioned on the shaft between the first and second balloons, having one agent delivery segment orifice formed therein, and an agent delivery lumen in fluid communication with said agent delivery segment orifice;

v) an aspiration segment positioned on the shaft between the first and second balloons and having one aspiration segment orifice formed therein;

vi) wherein said visualization means enables visualization of the lumen between the first and second balloons;

vii) a guidewire lumen formed within the shaft and in communication with;

an opening formed in the proximal end of the catheter; and

an opening formed in the shaft distal tip; and

b) said isolating further comprises inflating the first and second balloons.

11. The method of claim 10, wherein said catheter further comprises a visualization means lumen in communication with a visualization means slot, and wherein said visualization means extends through said visualization means lumen at least to said visualization means slot.

12. The method of claim 8, further comprising flushing the isolated treatment region.

13. The method of claim 8, further comprising evacuating the isolated treatment region.

14. The method of claim 8, further comprising evacuating the treatment region and flushing the treatment region.