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Antisense oligonucleotides for inducing exon skipping and methods of use thereof

  • US 9,018,368 B2
  • Filed: 06/26/2014
  • Issued: 04/28/2015
  • Est. Priority Date: 06/28/2004
  • Status: Active Grant
First Claim
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1. An antisense oligonucleotide of 30 bases comprising the base sequence CUCCAACAUC AAGGAAGAUG GCAUUUCUAG (SEQ ID NO:

  • 181), in which the uracil bases are thymine bases, wherein the antisense oligonucleotide is a morpholino antisense oligonucleotide, and wherein the antisense oligonucleotide is chemically linked to a polyethylene glycol chain.

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