Electrical stimulator with voltage mode emulation using regulated current

• US 9,020,589 B2
• Filed: 04/27/2010
• Issued: 04/28/2015
• Est. Priority Date: 04/27/2010
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Torgerson, Nathan A.
• Primary Examiner(s): Gedeon, Brian T
• Assistant Examiner(s): Tejani, Ankit
• Application Number:
  US12/768,309
• Publication Number:
  US 20110264171A1
• Time in Patent Office: 1,827 Days
• Field of Search: 607 45- 46
• US Class Current: 607/2
• CPC Class Codes: A61N 1/36 for stimulation
• CPC Class Codes: A61N 1/3605 Implantable neurostimulators for stimulating central or peripheral nerve system
• CPC Class Codes: A61N 1/36146 specified by the stimulation parameters

Abstract

Techniques are described for generating electrical stimulation current pulses for delivery of electrical stimulation therapy via a current-controlled system that emulates voltage pulses generated via a voltage-controlled system. In one example, a method includes receiving user input specifying a voltage level of electrical stimulation to be delivered by one or more of a plurality of electrodes implanted within the patient, selectively coupling the one or more electrodes to respective regulated current paths to deliver the electrical stimulation to the patient, selectively coupling at least another of the plurality of electrodes implanted within the patient to an unregulated current path to deliver the electrical stimulation to the patient, determining a regulated current for each respective regulated current path in order to produce the specified voltage level at the one or more electrodes selectively coupled to the respective regulated current paths, and delivering the determined regulated currents via the respective regulated current paths.

Claims

1. A method for controlling a system for delivering electrical stimulation therapy, the method comprising:

receiving user input specifying a voltage level of electrical stimulation to be delivered by one or more of a plurality of electrodes of the system, wherein the electrodes are implanted within the patient;

selectively coupling, by a stimulation controller of a stimulation generator of the system, the one or more electrodes to respective regulated current paths to deliver the electrical stimulation to the patient;

selectively coupling, by the stimulation controller, at least another of the plurality of electrodes implanted within the patient to an unregulated current path to deliver the electrical stimulation to the patient;

generating, by one or more current regulators of the stimulation generator of the system, regulated currents for the regulated current paths;

determining, by a processor of the system, the regulated current for each respective regulated current path in order to produce the specified voltage level at the one or more electrodes selectively coupled to the respective regulated current paths such that the system emulates a voltage mode system; and

controlling, by the processor, the stimulation generator to deliver the determined regulated currents via the respective regulated current paths.

2. The method of claim 1,

wherein selectively coupling the one or more electrodes to respective regulated current paths to deliver the electrical stimulation to the patient comprises:

coupling a first electrode to a first regulated current path to deliver a first amount of the electrical stimulation current; and

coupling a second electrode to a second regulated current path to deliver a second amount of the electrical stimulation current, and

wherein selectively coupling at least another of the plurality of electrodes implanted within the patient to an unregulated current path to deliver the electrical stimulation to the patient comprises;

coupling a third electrode to the unregulated current path to deliver a third amount of the electrical stimulation current approximately equal to a sum of the first and second amounts of the electrical stimulation current, wherein the unregulated current path is coupled to a reference voltage.

3. The method of claim 1, wherein at least some of the plurality of electrodes are carried by one or more leads implanted within the patient.

4. The method of claim 1, further comprising coupling the electrodes to the regulated and unregulated current paths on a selective basis to form different electrode configurations.

5. The method of claim 1, wherein determining a regulated current for each respective regulated current path in order to produce the specified voltage level at the one or more electrodes selectively coupled to the respective regulated current paths comprises:

delivering a first electrical current via a first electrode of the one or more electrodes selectively coupled to the respective regulated current paths;

measuring a voltage difference value between the first electrode and one of the plurality of electrodes coupled to the unregulated current path;

calculating an impedance value between the first electrode and the one of the plurality of electrodes coupled to an unregulated current path based on the first electrical current and the measured voltage difference value; and

determining the regulated current based on the calculated impedance value.

6. The method of claim 1, wherein determining a regulated current for each respective regulated current path in order to produce the specified voltage level at the one or more electrodes selectively coupled to the respective regulated current paths comprises:

delivering a first electrical current via a first electrode of the one or more electrodes selectively coupled to the respective regulated current paths;

measuring a voltage at the first electrode; and

adjusting the first electrical current in response to the measured voltage.

7. The method of claim 1, wherein delivering the determined regulated currents via the respective regulated current paths comprises:

generating one of the determined regulated currents via a respective current regulator, the one of the determined regulated currents having a pulse current level, a pulse voltage level, and a pulse width;

controlling the pulse current level to decrease during the pulse width; and

delivering the one of the determined regulated currents pulse via one or more implantable electrodes.

8. The method of claim 7, wherein generating one of the determined regulated currents via a respective current regulator comprises generating one of the determined regulated currents having first and second sub-pulses, the second sub-pulse following the first sub-pulse in time, wherein the pulse current level of the second sub-pulse is less than the pulse current level of the first sub-pulse.

9. A system for delivering electrical stimulation therapy, the system comprising:

a plurality of implantable electrodes;

a stimulation generator comprising;

a stimulation controller configured to;

selectively couple one or more of the plurality of implantable electrodes to respective regulated current paths to deliver electrical stimulation to a patient, and

selectively couple at least another of the plurality of implantable electrodes to an unregulated current path to deliver the electrical stimulation to the patient; and

one or more current regulators configured to generate regulated currents for the regulated current paths; and

a processor configured to;

receive user input from a user specifying a voltage level of the electrical stimulation to be delivered by the one or more of the plurality of electrodes;

determine the regulated current for each respective regulated current path in order to produce the specified voltage level at the one or more electrodes selectively coupled to the respective regulated current paths such that the system emulates a voltage mode system; and

control the stimulation generator to deliver the determined regulated currents via the one or more current regulators and the respective regulated current paths.

10. The system of claim 9,

wherein the stimulation controller configured to selectively couple the one or more electrodes to respective regulated current paths to deliver the electrical stimulation to the patient is further configured to:

couple a first electrode to a first regulated current path to deliver a first amount of the electrical stimulation current; and

couple a second electrode to a second regulated current path to deliver a second amount of the electrical stimulation current, and

wherein the stimulation controller configured to selectively couple at least another of the plurality of electrodes implanted within the patient to an unregulated current path to deliver the electrical stimulation to the patient is further configured to;

couple a third electrode to the unregulated current path to deliver a third amount of the electrical stimulation current approximately equal to a sum of the first and second amounts of the electrical stimulation current, wherein the unregulated current path is coupled to a reference voltage.

11. The system of claim 9, wherein at least some of the plurality of electrodes are carried by one or more leads implanted within the patient.

12. The system of claim 9, wherein the stimulation controller is further configured to couple the electrodes to the regulated and unregulated current paths on a selective basis to form different electrode configurations.

13. The system of claim 9, wherein the processor configured to determine the regulated current for each respective regulated current path in order to produce the specified voltage level at the one or more electrodes selectively coupled to the respective regulated current paths is further configured to:

control the stimulation generator to deliver a first electrical current via a first electrode of the one or more electrodes selectively coupled to the respective regulated current paths;

control measurement of a voltage difference value between the first electrode and one of the plurality of electrodes coupled to the unregulated current path;

calculate an impedance value between the first electrode and the one of the plurality of electrodes coupled to an unregulated current path based on the first electrical current and the measured voltage difference value; and

determine the regulated current based on the calculated impedance value.

14. The system of claim 9, wherein the processor configured to determine the regulated current for each respective regulated current path in order to produce the specified voltage level at the one or more electrodes selectively coupled to the respective regulated current paths is further configured to:

control the stimulation generator to deliver a first electrical current via a first electrode of the one or more electrodes selectively coupled to the respective regulated current paths;

control measurement of a voltage at the first electrode; and

control the stimulation generator to adjust the first electrical current in response to the measured voltage.

15. The system of claim 9, wherein the processor configured to control the stimulation generator to deliver the determined regulated currents via the one or more current regulators and the respective regulated current paths is further configured to:

control the stimulation generator to generate one of the determined regulated currents via a respective one of the current regulators, the one of the determined regulated currents having a pulse current level, a pulse voltage level, and a pulse width;

control the stimulation generator to control the pulse current level to decrease during the pulse width; and

control the stimulation generator to deliver the one of the determined regulated currents via one or more implantable electrodes.

16. The system of claim 15, wherein the processor configured to control the stimulation generator to generate one of the determined regulated currents via the respective current regulator is further configured to control the stimulation generator to generate one of the determined regulated currents having first and second sub-pulses, the second sub-pulse following the first sub-pulse in time, wherein the pulse current level of the second sub-pulse is less than the pulse current level of the first sub-pulse.

18. The system of claim 9, wherein the processor is configured to determine the regulated current to produce the specified voltage level based on a measured voltage at one of the electrodes.

19. The system of claim 18, wherein the processor is configured to control measurement of the measured voltage during delivery of the regulated current.

20. The system of claim 9, wherein the processor is configured to determine the regulated current to produce the specified voltage level based on an impedance measured between two of the electrodes.

21. The system of claim 20, wherein the processor is configured to control measurement of the measured impedance during delivery of the regulated current.

22. The system of claim 9, wherein the at least another of the plurality of electrodes coupled to an unregulated current path is an anode.

17. A device for delivering electrical stimulation therapy, the device comprising:

means for receiving user input specifying a voltage level of electrical stimulation to be delivered by one or more of a plurality of electrodes implanted within the patient;

means for selectively coupling the one or more electrodes to respective regulated current paths to deliver the electrical stimulation to the patient;

means for selectively coupling at least another of the plurality of electrodes implanted within the patient to an unregulated current path to deliver the electrical stimulation to the patient;

means for determining a regulated current for each respective regulated current path in order to produce the specified voltage level at the one or more electrodes selectively coupled to the respective regulated current paths such that the device emulates a voltage mode device;

means for generating the regulated current for each respective regulated current path; and

means for delivering the determined regulated currents via the respective regulated current paths.