Delivery system for injection through zone of body

• US 9,022,987 B2
• Filed: 11/17/2011
• Issued: 05/05/2015
• Est. Priority Date: 07/07/2008
• Status: Active Grant

• Current Assignee: Gabriel Institute, Inc.
• Original Assignee: Gabriel Institute, Inc.
• Inventors: Stearns, Stanley D., Loy, H. Max Jr., Davis, Donald G.
• Primary Examiner(s): Bosques, Edelmira
• Application Number:
  US13/298,742
• Publication Number:
  US 20120065618A1
• Time in Patent Office: 1,265 Days
• Field of Search: 604/191, 604/187, 604/506, 604194-195
• US Class Current: 604/187
• CPC Class Codes: A61M 2202/049 Toxic
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 2206/20 having means for promoting or enhancing the flow, actively or passively
• CPC Class Codes: A61M 5/16886 for measuring fluid flow rate, i.e. flowmeters
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: A61M 5/1785 comprising radioactive shield means syringe shields or holders for storage of radioactive sources G21F5/018
• CPC Class Codes: A61M 5/2053 Media being expelled from injector by pressurised fluid or vacuum for infusion A61M5/145, A61M5/155
• CPC Class Codes: A61M 5/32 Needles; Details of needles pertaining to their connection with syringe or hub infusion needles A61M5/158; Accessories for bringing the needle into, or holding the needle on, the body A61M5/42, A61M5/46 take precedence; guide needles for catheters A61M25/065; Devices for protection of needles apparatus specially adapted for cleaning or sterilising needles A61M5/001
• CPC Class Codes: A61M 5/46 having means for controlling depth of insertion
• CPC Class Codes: A61M 5/484 Regulating injection pressure

Abstract

A dispensing device which disperses medicate through a needle across a zone within a body with zero pressure differential. The device includes a needle which is, during use, becomes encapsulated within a tubular needle-receiving member, a therapeutic agent reservoir in fluid communication with the needle, positioned within said housing, and in communication with the needle, a second reservoir, a reservoir-connecting conduit in communication with the therapeutic agent reservoir, a fluid drive in communication with the fluid in the second reservoir and in communication with said reservoir-connecting conduit, and a linear drive attached to said needle or to said needle-receiving member.

Claims

1. A distributed injection device, comprising

a needle, said needle having an attachment end and an injection end, said needle having a needle outer diameter, and said needle having an internal cross-sectional area, said needle having a needle longitudinal axis;

a housing including a needle-receiving member, said needle-receiving member being tubular, said needle-receiving member having an open first end, said needle-receiving member having a needle-receiving member inner diameter, said needle-receiving member inner diameter greater than said needle outer diameter, said needle-receiving member having a needle-receiving member longitudinal axis, said needle longitudinal axis and said needle-receiving member longitudinal axis generally parallel, said needle-receiving member circumscribing said needle longitudinal axis;

a therapeutic agent reservoir adapted to contain a therapeutic agent, said therapeutic agent reservoir in fluid communication with said needle via a tubing, said therapeutic agent reservoir positioned within said housing;

a second reservoir adapted to contain fluid;

a reservoir-connecting conduit, said reservoir-connecting conduit in communication with said therapeutic agent reservoir;

a fluid drive in communication with said fluid in said second reservoir, said fluid drive in communication with said reservoir-connecting conduit; and

a linear drive associated with said needle or said needle-receiving member;

said linear drive adapted to provide a linear displacement of said needle towards said housing, or to provide a linear displacement of said needle-receiving member away from said housing, the product of said linear displacement and internal cross-sectional area of said needle providing a volume of displacement, said volume of displacement per unit time providing a flow rate;

wherein said fluid drive adapted to impel fluid from said second reservoir to said reservoir-connecting conduit and to drive said therapeutic agent from said therapeutic agent reservoir at said flow rate during said linear displacement of said needle towards said housing, and

wherein said fluid communication from said therapeutic agent reservoir to said needle is maintained by said tubing during operation of said linear drive to provide a linear displacement of said needle towards said housing, or to provide a linear displacement of said needle-receiving member away from said housing.

2. The distributed injection device of claim 1 further comprising

a slide member, said needle fixed in position at a first end of said slide member,

said slide member slidably positioned within said receiving member;

and

said linear drive connected to said slide member.

3. A method for a distributed injection into a body from a reservoir of therapeutic agent, comprising:

driving a needle into said body, said needle having an internal cross-sectional area;

retracting said needle from said body at a fixed velocity by a linear drive into a housing including a needle receiving member, said needle being encapsulated by said needle-receiving member during retraction, the product of said velocity and said cross-sectional area providing a flow rate;

impelling fluid from a second reservoir through a reservoir-connecting conduit to a therapeutic agent reservoir containing said therapeutic agent at said flow rate;

commencing impelling said therapeutic agent from said therapeutic agent reservoir to said needle by displacement by said fluid at said flow rate upon beginning retracting said needle from said body at a fixed velocity; and

delivering said therapeutic agent from said needle into said body at zero pressure differential after commencing impelling said therapeutic agent from said therapeutic agent reservoir.