Infusion treatment agents, catheters, filter devices, and occlusion devices, and use thereof

• US 9,023,010 B2
• Filed: 10/24/2007
• Issued: 05/05/2015
• Est. Priority Date: 03/12/2003
• Status: Expired due to Fees

• Current Assignee: Advanced Cardiovascular Systems Incorporated
• Original Assignee: Advanced Cardiovascular Systems Incorporated
• Inventors: Chiu, Jessica G., Chan, Gregory Waimong, Asongwe, Gabriel, Esselstein, Robert C., Gesswein, Douglas, Sridharan, Srinivasan, Bei, Nianjiong Joan, Webler, William E., Schaible, Stephen G., Chow, Mina, Shen, Yan, Bai, Hongzhi, Bly, Mark J., Hatten, Thomas R.
• Primary Examiner(s): Berdichevsky, Aarti B
• Assistant Examiner(s): SCHELL, LAURA C
• Application Number:
  US11/923,068
• Publication Number:
  US 20080103478A1
• Time in Patent Office: 2,750 Days
• Field of Search: 604/508, 604/509, 604/510, 604/523, 604/528, 604/532
• US Class Current: 604/509
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 25/10 Balloon catheters A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02; inflatable balloons for placing stents or stent-grafts A61F2/958 ; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00
• CPC Class Codes: A61M 25/1002 characterised by balloon shape A61M25/1006, A61M25/1009 take precedence

Abstract

Embodiments include an infusion-occlusion system having a delivery catheter, a guide catheter adapted to receive the delivery catheter, and a guidewire with an occlusion device adapted to be received within the guide catheter. The guide catheter of the catheter kit may be provided with an occlusion device at the distal end of the guide catheter. The delivery catheter may have an accessory lumen, coaxial or co-linear lumen, a supporting mandrel, or an occlusion device at its distal end. Moreover, according to some embodiments, occlusion devices may be a single material or a composite balloon having an inner liner and an outer layer of different materials, a high compliance low pressure balloon, or a filter device that restricts particles from passing through but does not restrict fluid, such as blood. An inflation device with a large volume and low volume syringe can be used to inflate the balloon.

Claims

1. A method comprising:

accessing a vessel selected from the group consisting of external femoral, interior femoral, carotid, jugular, brachial, subclavian, or cephalic with a guide catheter;

then

accessing a coronary sinus with the guide catheter;

then

feeding a retroinfusion balloon catheter and a guidewire with an occlusion device at a distal end of the guidewire to the coronary sinus, great cardiac vein, posterior vein of left ventricle, middle cardiac vein, small cardiac vein, or anterior cardiac vein of right ventricle through a lumen of the guide catheter;

then

performing a venogram, wherein performing the venogram comprises injecting a dye into and visualizing one or more target vessels;

then

deploying the guidewire and the balloon catheter to the one or more targeted vessels, wherein deploying comprises advancing the guidewire into the one or more target vessels, and then threading the balloon catheter over the guidewire to the one or more target vessels;

then

measuring a baseline parameter in a vein adjacent to a distal end of the balloon catheter, wherein the baseline parameter comprises one of pressure, flow, oxygen saturation, pH, or temperature;

then

inflating a balloon at the distal end of the balloon catheter and engaging the occlusion device at the distal end of the guidewire, wherein inflating the balloon is sufficient to make a pressure waveform in the vein become ventricularized;

after inflating the balloon and after engaging the occlusion device, delivering a liquid comprising at least one of a drug and a treatment agent through the balloon catheter to an outlet port on the balloon catheter distal to the balloon and proximal to the occlusion device; and

then

performing an infusate-uptake-enhancing procedure, wherein the infusate-uptake-enhancing procedure is one of electroporation, ultrasonic excitation, or photodynamic therapy.

2. The method of claim 1 further comprising:

stopping the delivering of the liquid;

then

deflating the balloon and disengaging the occlusion device;

then

removing the catheter from the vessel; and

then

performing the infusate-uptake-enhancing procedure.

3. The method of claim 1 wherein the treatment agent comprises a drug or progenitor cells;

and wherein inflating, engaging and delivering occur in the same vein.

4. The method of claim 1, wherein the guidewire lumen is a separate and distinct lumen from the infusion lumen.

5. A method comprising:

accessing a vessel selected from the group consisting of external femoral, interior femoral, carotid, jugular, brachial, subclavian, or cephalic with a guide catheter;

then

accessing a coronary sinus with the guide catheter;

then

feeding a retroinfusion balloon catheter and a guidewire with an occlusion device at a distal end of the guidewire to the coronary sinus, great cardiac vein, posterior vein of left ventricle, middle cardiac vein, small cardiac vein, or anterior cardiac vein of right ventricle through a lumen of the guide catheter;

then

performing a venogram, wherein performing the venogram comprises injecting a dye into and visualizing one or more target vessels;

then

deploying the guidewire and the balloon catheter to the one or more targeted vessels;

measuring a baseline parameter in a vein adjacent to a distal end of the balloon catheter, wherein the baseline parameter comprises one of pressure, flow, oxygen saturation, pH, or temperature;

then

inflating a balloon at the distal end of the balloon catheter and engaging the occlusion device at the distal end of the guidewire, wherein inflating the balloon is sufficient to make a pressure waveform in the vein become ventricularized;

after inflating the balloon and after engaging the occlusion device, delivering a liquid comprising at least one of a drug and a treatment agent through the balloon catheter to an outlet port on the balloon catheter distal to the balloon and proximal to the occlusion device, wherein the guidewire exits a distal-most opening of a distal end of the guide catheter; and

then

performing an infusate-uptake-enhancing procedure, wherein the infusate-uptake-enhancing procedure is one of electroporation, ultrasonic excitation, or photodynamic therapy.

6. The method of claim 5, wherein the guidewire lumen is separate and distinct lumen from the infusion lumen.