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Hair follicle graft from tissue engineered skin

  • US 9,023,380 B2
  • Filed: 03/23/2010
  • Issued: 05/05/2015
  • Est. Priority Date: 11/22/2005
  • Status: Active Grant
First Claim
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1. A method of making a hair graft, comprising:

  • a) incubating a tissue engineered dermal layer on a bioabsorbable scaffold until the tissue engineered dermal layer attaches to the bioabsorable scaffold;

    b) placing hair follicle progenitor cells on the tissue engineered dermal layer;

    c) placing a tissue engineered epidermal layer comprising a sheet of keratinocytes on the hair follicle progenitor cells to form a construct;

    d) allowing the construct to mature in vitro; and

    e) cutting the construct into one or more implantable grafts.

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