Measurement of systolic pressure

• US 9,028,418 B2
• Filed: 12/03/2009
• Issued: 05/12/2015
• Est. Priority Date: 12/05/2008
• Status: Active Grant

• Current Assignee: ATYS Sarl
• Original Assignee: ATYS Sarl
• Inventors: Parzy, Denis, Guibert, Benoit
• Primary Examiner(s): D'ANGELO, MICHAEL J
• Application Number:
  US13/131,768
• Publication Number:
  US 20110282219A1
• Time in Patent Office: 1,986 Days
• Field of Search: 600481-507
• US Class Current: 600/490
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/02141 Details of apparatus construction, e.g. pump units or housings therefor, cuff pressurising systems, arrangements of fluid conduits or circuits A61B5/02233, A61B5/0235 take precedence
• CPC Class Codes: A61B 5/022 by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
• CPC Class Codes: A61B 5/02225 using the oscillometric method
• CPC Class Codes: A61B 5/02241 of small dimensions, e.g. adapted to fingers
• CPC Class Codes: A61B 5/02255 the pressure being controlled by plethysmographic signals, e.g. derived from optical sensors

Abstract

A noninvasive method for measuring systolic blood pressure P_syst, by applying and maintaining an astringent emptying pressure P1, which is above the systolic blood pressure P_syst, on a first zone of the finger located in the vicinity of the distal part of the finger, applying and maintaining an astringent occluding pressure P2, which is above the systolic blood pressure P_syst, on a second zone of the finger located upstream of the first zone, releasing the emptying pressure P1, releasing the occluding pressure P2 in a controlled manner, and, at the same time, acquiring at least the occluding pressure P2 and at least the blood volume V_s, at the level of the first zone as a function of time, and calculating the systolic blood pressure P_systcorresponding to the occluding pressure P2 at the moment of blood return in the finger, characterized by a substantially positive variation in the blood volume V_sof the finger at the level of the first zone.

Claims

1. A non-invasive method for measuring the systolic blood pressure of a digit having a distal part, the method comprising the steps of:

applying and maintaining an astringent draining pressure greater than the systolic blood pressure of the digit on a first region located in the vicinity of the distal part of the digit, to substantially drain the digit of blood in said distal part, followed by,

applying and maintaining an astringent occluding pressure greater than the systolic blood pressure of the digit on a second region of the digit located upstream of the first region,

releasing the draining pressure,

controllably releasing the occluding pressure, allowing blood to enter said drained distal region of the digit, and, at the same time, acquiring at least the occluding pressure and at least the blood volume of the digit at the first region as a function of time,

calculating the systolic blood pressure corresponding to the occluding pressure at the time of blood return to the digit characterized by a substantially positive variation in the blood volume of the digit at the first region;

wherein the systolic blood pressure is measured only during deflation.

2. The method according to claim 1, wherein the draining pressure is greater than the systolic blood pressure of the digit.

3. The method according to claim 1, wherein the draining and occlusion pressures are applied and released automatically.

4. The method according to claim 1, wherein the draining pressure is applied and released manually, and the occluding pressure is applied and released automatically.

5. The method according to claim 1, further comprising a waiting phase which lasts between 0and 5 s, wherein the waiting phase occurs after release of the draining pressure.

6. The method according to claim 1, wherein the step for calculating the systolic blood pressure comprises:

extracting a pulsatile component representing the pulsatile arterial flow in the digit, from the variation in blood volume of the digit at the first region as a function of time,

calculating the systolic blood pressure by determining the occluding pressure at the time of re-onset of the pulsatile component of the signal.

7. The method for measuring blood pressure according to claim 1, wherein the step for calculating systolic blood pressure comprises:

extracting a non-pulsatile component representing filling of the digit resulting from pulsatile arterial flow, from microcirculation and/or from non-pulsatile arterial flow, using the variation in blood volume of the digit at the first region as a function of time,

calculating systolic blood pressure by determining the occluding pressure at the time when the non-pulsatile component varies substantially positively.

8. The method according to claim 1, comprising adjusting the time needed for release of the occluding pressure so that release of the occluding pressure takes place over a fixed number of cardiac cycles.

16. The method according to claim 5, wherein the waiting phase lasts in the order of 3 seconds.

17. The method according to claim 1, wherein the astringent occluding pressure is applied and maintained at a pressure greater than 30 mmHg.

18. The method according to claim 5, wherein a minimum value of the systolic blood pressure measured is 10 mmHg.

9. A non-invasive device for measuring the systolic blood pressure of a digit having a distal part, the device comprising:

a first element comprising a sensor configured to measure the blood volume of a digit at a first region located in the vicinity of the distal part of the digit, and a draining member configured to apply or transmit a draining pressure, that is greater than the systolic blood pressure of the digit, to the first region of the digit, and to substantially drain the digit of blood in said distal part,

a second element comprising an arterial occluding member configured to apply and/or maintain an occluding pressure on a second region of the digit located upstream of the first region, to allow blood to enter the drained distal part of the digit, and

a servo-controlled inflating and deflating device controlled by control electronics and ensuring the inflation and deflation of at least the arterial occluding member,

a pressure measurement system measuring at least the pressure applied by the arterial occluding member,

and a processing system controlled by the control electronics and comprising;

an acquisition stage which acquires at least the data delivered by the pressure measurement system (16) and by the sensor,

a processing unit comprising;

means for determining the time when the blood volume of the digit at the first region varies substantially positively,

means for calculating systolic blood pressure corresponding to the occluding pressure at the time when the blood volume in the digit at the first region varies substantially positively;

wherein the device is configured to measure the systolic blood pressure only during deflation.

10. The device according to claim 9, wherein the inflating and deflating device also ensures the inflation and deflation of the draining member.

11. The device according to claim 9, wherein at least the occluding member is formed of an air chamber.

12. The device according to claim 9, wherein the processing unit further comprises:

means for extracting a pulsatile component representing the pulsatile arterial flow in the digit (2) at the first region as a function of time,

means for determining the time of re-onset of the pulsatile component of the signal,

means for calculating the systolic blood pressure corresponding to the occluding pressure at the time of re-onset of the pulsatile component of the signal.

13. The device according to claim 9, wherein the processing unit further comprises:

means for extracting a non-pulsatile component representing filling of the digit resulting from pulsatile arterial flow, from microcirculation and/or from non-pulsatile arterial flow, as a function of time,

means for determining the time when the non-pulsatile component varies substantially positively,

means for calculating the systolic blood pressure corresponding to the occluding pressure at the time when the non-pulsatile component varies substantially positively.

14. The device according to claim 9, wherein the processing unit comprises comparison means between the value of the occluding pressure and a minimum value of the systolic blood pressure measured by the device.

15. The device according to claim 9, wherein the control electronics drive:

the inflating and deflating device to apply the draining pressure before application of the occluding pressure,

the inflating and deflating device, to release the draining pressure after application of the occluding pressure and before the controlled release of the occluding pressure,

the acquisition stage to acquire, during the controlled release of the occluding pressure, at least the data delivered by the pressure measurement system and by the sensor,

the processing unit to calculate the systolic pressure during the controlled release of the occluding pressure and at the time of detection of blood return into the digit.