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Chitosan-derivative compounds and methods of controlling microbial populations

  • US 9,029,351 B2
  • Filed: 01/13/2014
  • Issued: 05/12/2015
  • Est. Priority Date: 06/02/2006
  • Status: Active Grant
First Claim
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1. An oral care method for controlling microbial activity in an individual comprising administering functionalized chitosan-arginine compounds that are soluble at physiologic pH, in a therapeutically effective amount and in a therapeutically effective excipient, wherein the compounds are between 2% and 50% functionalized;

  • are substantially free of compounds having a molecular weight of less than 5000 Da, and wherein the compounds are substantially free of polyarginine polymers.

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