Methods and systems for treating seizures caused by brain stimulation

• US 9,031,656 B2
• Filed: 11/06/2013
• Issued: 05/12/2015
• Est. Priority Date: 12/26/2007
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Whitehurst, Todd K., Carbunaru, Rafael, Jaax, Kristen N., DiGiore, Andrew, Schleicher, Brett, Baldwin, Greg
• Primary Examiner(s): GETZOW, SCOTT M
• Application Number:
  US14/073,798
• Publication Number:
  US 20140067004A1
• Time in Patent Office: 552 Days
• Field of Search: 600/544, 600/545, 607/45
• US Class Current: 607/45
• CPC Class Codes: A61N 1/0529 Electrodes for brain stimulation
• CPC Class Codes: A61N 1/0534 Electrodes for deep brain stimulation
• CPC Class Codes: A61N 1/36064 Epilepsy
• CPC Class Codes: A61N 1/36082 Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
• CPC Class Codes: A61N 1/37205 Microstimulators, e.g. implantable through a cannula
• CPC Class Codes: A61N 1/3756 Casings with electrodes thereon, e.g. leadless stimulators

Abstract

Methods for treating seizures caused by brain stimulation include providing a stimulator, programming the stimulator with one or more stimulation parameters configured to treat a medical condition, applying at least one stimulus with the stimulator to a stimulation site within the brain of a patient in accordance with the one or more stimulation parameters, and monitoring the patient for a seizure caused by the at least one stimulus.

Claims

1. A system for treating a patient having a medical condition, comprising:

a memory unit configured for storing one or more stimulation parameters;

a stimulator configured for applying at least one stimulus to a stimulation site within the brain of the patient in accordance with the one or more stimulation parameters, thereby treating the medical condition;

a monitoring unit configured for detecting an event indicative of one of an impending seizure caused by the at least one stimulus before the seizure actually occurs and an actual seizure caused by the at least one stimulus; and

an anti-seizure unit configured for directing the stimulator to apply an asynchronous electrical stimulation pattern to a location of the brain to prevent the actual seizure from occurring or to treat the actual seizure.

2. The system of claim 1, wherein the event is indicative of the impending seizure, and the anti-seizure unit is configured for directing the stimulator to apply the asynchronous electrical stimulation pattern to the location of the brain to prevent the actual seizure from occurring.

3. The system of claim 1, wherein the event is indicative of the actual seizure, and the anti-seizure unit is configured for directing the stimulator to apply the asynchronous electrical stimulation pattern to the location of the brain to treat the actual seizure.

4. The system of claim 1, wherein the event indicative of the impending seizure or the actual seizure is a brain wave having a synchronous pattern.

5. The system of claim 1, wherein the at least one stimulus comprises a synchronous electrical stimulation pattern, and wherein the stimulator is configured for applying the asynchronous electrical stimulation pattern by switching from the synchronous electrical stimulation pattern to the asynchronous electrical stimulation pattern.

6. The system of claim 1, wherein the stimulator is further configured for warning the patient of the detection of the event indicative of the impending seizure or the actual seizure.

7. The system of claim 1, wherein the at least one stimulus comprises at least one of an electrical stimulus and an infusion of one or more drugs.

8. The system of claim 1, wherein the stimulator is implantable.