Wireless neural recording and stimulating system
First Claim
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1. A neurostimulation system for mitigating pain comprising:
- at least one implantable sensor that is configured to measure a neuronal signal from a first neuron and to wirelessly transmit the neuronal signal;
at least one implantable stimulator configured to wirelessly receive a stimulation command signal, wherein the implantable stimulator is configured to generate an electrical signal in response to the stimulation command signal, wherein the generated electrical signal is configured to be applied directly to a second neuron to alter neural activity at the first neuron, wherein the first neuron and the second neuron are on a neural pathway, wherein the neural pathway includes at least one of a spinal-thalamus-somatosensory pathway and a cortico-ponto-spinal decending pathway; and
a remote processing device configured to;
receive the wirelessly transmitted neuronal signal from the implantable sensor;
receive a selection of a pain threshold based on input from a patient;
determine a pain level based on the wirelessly transmitted neuronal signal;
determine a stimulation command signal based on the determined pain level and the selected pain threshold; and
wirelessly transmit the stimulation command signal to the implantable stimulator.
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Abstract
Apparatus and methods are provided for the management of neural activity in an individual. Nerve activity is sensed and correlated with sensations such as pain. In response and without requiring input from the individual, although external input is contemplated, a signal is transmitted to another component for electrical stimulation that alters neural activity. Also, the modulation of the signals between the sensor and stimulator may be modified by a third component independently, independent of, or including user inputs.
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Citations
20 Claims
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1. A neurostimulation system for mitigating pain comprising:
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at least one implantable sensor that is configured to measure a neuronal signal from a first neuron and to wirelessly transmit the neuronal signal; at least one implantable stimulator configured to wirelessly receive a stimulation command signal, wherein the implantable stimulator is configured to generate an electrical signal in response to the stimulation command signal, wherein the generated electrical signal is configured to be applied directly to a second neuron to alter neural activity at the first neuron, wherein the first neuron and the second neuron are on a neural pathway, wherein the neural pathway includes at least one of a spinal-thalamus-somatosensory pathway and a cortico-ponto-spinal decending pathway; and a remote processing device configured to; receive the wirelessly transmitted neuronal signal from the implantable sensor; receive a selection of a pain threshold based on input from a patient; determine a pain level based on the wirelessly transmitted neuronal signal; determine a stimulation command signal based on the determined pain level and the selected pain threshold; and wirelessly transmit the stimulation command signal to the implantable stimulator. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A method of electrical neurostimulation to mitigate pain comprising the steps:
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recording a neuronal signal from a first neuron with an implanted sensor, wherein first neuron is on a neural pathway, wherein the neural pathway includes at least one of a spinal-thalamus-somatosensory pathway and a cortico-ponto-spinal decending pathway; and wirelessly transmitting the recorded neuronal signal to a remote processing device, by the remote processing device; receiving a selection of a pain threshold based on input from a patient; determining a pain level based on the wirelessly transmitted neuronal signal; determining a stimulation command signal based on the determined pain level and the selected pain threshold; and wirelessly transmitting the stimulation command signal to an implantable stimulator, wherein the implantable stimulator is configured to apply an electrical signal directly to a second neuron, wherein the second neuron is on the neural pathway; and by the stimulator, generating an electrical signal in response to the stimulation command signal, wherein the electrical signal is configured to alter neural activity at the first neuron. - View Dependent Claims (16, 17, 18, 19, 20)
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Specification