System for transvascularly stimulating autonomic targets
First Claim
1. A system, comprising:
- an implantable first structure and a separately implantable second structure, each of the first and second structures configured to be intravascularly implanted within a patient;
intravascular electrodes, wherein the first structure includes at least a first one of the intravascular electrodes and the second structure includes at least a second one of the intravascular electrodes;
a neural stimulator configured to generate neural stimulation signals for delivery through the intravascular electrodes to transvascularly stimulate at least two autonomic neural targets, the at least two autonomic neural stimulation targets including a first autonomic neural stimulation target at a first neural stimulation site and a second autonomic neural stimulation target at a second neural stimulation site separate from the first neural stimulation site, the neural stimulator configured to use;
at least the first one of the intravascular electrodes to transvascularly stimulate the first neural stimulation target at the first neural stimulation site, wherein the first one of the intravascular electrodes is not used to transvascularly stimulate the second neural stimulation target at the second neural stimulation site; and
at least the second one of the intravascular electrodes to transvascularly stimulate the second neural stimulation target at the second neural stimulation site, wherein the second one of the intravascular electrodes is not used to transvascularly stimulate the first neural stimulation target at the first neural stimulation site, the at least two autonomic neural stimulation targets including at least one baroreceptor region or at least one autonomic nerve target; and
an anchor structure configured to chronically and securely implant both the neural stimulator and the intravascular electrodes within vasculature of the patient and operably position the intravascular electrodes to stimulate the at least two autonomic neural targets.
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Abstract
Various implantable medical device embodiments stimulate an autonomic neural target from within a pulmonary artery, and comprise at least one electrode, a power supply, a neural stimulator connected to the power supply, and an anchor structure. The neural stimulator is configured to generate a neural stimulation signal for delivery to the neural stimulation target through the at least one electrode. The anchor structure is configured to chronically and securely implant the neural stimulator, the power supply and the at least one electrode within the pulmonary artery. The anchor structure, the neural stimulator, the power supply and the at least one electrode are configured to be implanted through a pulmonary valve into the pulmonary artery. In various embodiments, the neural stimulator is configured to be operational to implement a neural stimulation protocol when chronically implanted within the pulmonary artery without a wired connection through the pulmonary valve.
94 Citations
10 Claims
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1. A system, comprising:
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an implantable first structure and a separately implantable second structure, each of the first and second structures configured to be intravascularly implanted within a patient; intravascular electrodes, wherein the first structure includes at least a first one of the intravascular electrodes and the second structure includes at least a second one of the intravascular electrodes; a neural stimulator configured to generate neural stimulation signals for delivery through the intravascular electrodes to transvascularly stimulate at least two autonomic neural targets, the at least two autonomic neural stimulation targets including a first autonomic neural stimulation target at a first neural stimulation site and a second autonomic neural stimulation target at a second neural stimulation site separate from the first neural stimulation site, the neural stimulator configured to use; at least the first one of the intravascular electrodes to transvascularly stimulate the first neural stimulation target at the first neural stimulation site, wherein the first one of the intravascular electrodes is not used to transvascularly stimulate the second neural stimulation target at the second neural stimulation site; and at least the second one of the intravascular electrodes to transvascularly stimulate the second neural stimulation target at the second neural stimulation site, wherein the second one of the intravascular electrodes is not used to transvascularly stimulate the first neural stimulation target at the first neural stimulation site, the at least two autonomic neural stimulation targets including at least one baroreceptor region or at least one autonomic nerve target; and an anchor structure configured to chronically and securely implant both the neural stimulator and the intravascular electrodes within vasculature of the patient and operably position the intravascular electrodes to stimulate the at least two autonomic neural targets. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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Specification