Determining catheter status

• US 9,033,920 B2
• Filed: 03/11/2010
• Issued: 05/19/2015
• Est. Priority Date: 10/02/2003
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Miesel, Keith A.
• Primary Examiner(s): Lucchesi, Nicholas
• Assistant Examiner(s): CHANDER, DIVA KAKAR
• Application Number:
  US12/721,647
• Publication Number:
  US 20100168607A1
• Time in Patent Office: 1,895 Days
• Field of Search: 604/131, 604/65, 604/67, 604/891.1, 604/111
• US Class Current: 604/111
• CPC Class Codes: A61M 2005/1726 the body parameters being measured at, or proximate to, the infusion site
• CPC Class Codes: A61M 2202/0464 Cerebrospinal fluid
• CPC Class Codes: A61M 27/006 Cerebrospinal drainage; Accessories therefor, e.g. valves
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/16859 Evaluation of pressure response, e.g. to an applied pulse

Abstract

A method for monitoring the status of an implanted catheter includes monitoring changes in pressure within a lumen of a catheter associated with physiological parameters (“physiological pressure”) and changes in pressure within the lumen of the catheter associated with bolus infusion of fluid into the catheter or bolus withdrawal of infusion from the catheter (“bolus pressure”). Methods that employ monitoring both physiological pressure and bolus pressure can provide information that cannot be obtained from monitoring physiological pressure or bolus pressure alone.

Claims

1. A method for determining status of an implanted catheter, the catheter having a delivery region intended to be positioned in a target location of a patient, the delivery region being in communication with a lumen of the catheter, the method comprising:

measuring pressure within the lumen of the catheter;

developing a physiological pressure modulation profile based on the measured pressure;

infusing or withdrawing a bolus of fluid into or from the lumen of the catheter;

measuring pressure within the lumen of the catheter created by the bolus;

developing a bolus pressure modulation profile based on the measured bolus pressure; and

determining the status of the catheter by comparing the developed bolus pressure modulation profile to a predetermined bolus pressure profile and by comparing the developed physiological pressure modulation profile to a predetermined physiological pressure profile of the target location.

2. The method of claim 1, further comprising (i) determining whether the developed bolus pressure modulation profile is indicative of a catheter complication, and (ii) determining whether the developed physiological pressure modulation profile is indicative of a catheter complication.

3. The method of claim 2, wherein the target location is a cerebrospinal fluid compartment and wherein the method further comprises:

determining that the delivery region of the catheter has migrated out of the cerebrospinal fluid compartment if (i) the developed physiological pressure modulation profile is determined to be indicative of a catheter complication, and (ii) the developed bolus pressure modulation profile is determined to not be indicative of a catheter complication.

4. The method of claim 2, wherein the target location is a cerebrospinal fluid compartment and wherein the method further comprises:

determining that the catheter has a leak within the cerebrospinal fluid compartment if (i) the developed physiological pressure modulation profile is determined not to be indicative of a catheter complication, and (ii) the developed bolus pressure modulation profile is determined to be indicative of a catheter complication, wherein the catheter complication is determined to be a leak based on the developed bolus pressure modulation profile.

5. The method of claim 1, wherein the developed bolus pressure modulation profile is based on withdrawal of a bolus from the catheter.

6. The method of claim 5, further comprising determining that the delivery region is adjacent a solid tissue if the developed bolus pressure modulation profile is indicative of an occlusion.

7. The method of claim 6, further comprising developing a second bolus pressure modulation profile based on infusion of a bolus into the catheter, and determining whether the developed second bolus pressure modulation profile is indicative of an occlusion.

8. The method of claim 7, further comprising supporting the determination that the delivery region is adjacent a solid tissue if the developed second bolus pressure modulation profile is not indicative of an occlusion.

9. The method of claim 2, further comprising providing an alert if one or both of the developed physiological pressure modulation profile and the developed bolus pressure modulation profile are determined to be indicative of a catheter complication.

10. The method of claim 1, wherein each step of the method is carried out via an implantable infusion device operably coupled to the catheter.

11. A computer readable medium comprising instructions that cause an implantable infusion device to carry out the method of claim 1.

12. An implantable infusion device comprising the computer readable medium of claim 11 and configured to carry out the instructions.

13. The method of claim 1, wherein comparing the developed physiological pressure modulation profile to the predetermined physiological pressure modulation profile comprises determining whether the developed physiological pressure modulation profile has characteristics associated with patient respiration or heartbeat.