Method of using an anti-growth matrix as a barrier for cell attachment and osteo-inductive factors
First Claim
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1. A method for repairing an intervertebral disc comprising:
- forming a hole in an annulus fibrosis;
removing damaged annulus fibrosis or nucleus pulposus material from an intervertebral disc space of an intervertebral disc;
inserting an interbody fusion implant that does not contain an osteogenic inhibitory agent into the intervertebral disk space; and
closing the hole formed in the annulus fibrosis at least in part by delivering a growth-inhibiting matrix in or about the hole, the growth-inhibiting matrix adapted to prevent tissue or growth agents associated with the implant from migrating into areas outside the intervertebral disk space, and the growth-inhibiting matrix does not contain growth agents and comprises a bio-active additive that is present in an amount of about 1% to 10% of the total growth-inhibiting matrix volume.
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Abstract
The present invention generally relates to a method of using a matrix as a barrier for unwanted cell attachment and bone formation in unwanted areas of the human body during implant procedures. More specifically, a growth-inhibiting matrix may be used to prevent migration of osteo-inductive agents or bone tissue from an intervertebral disc space through the outer bands of annulus fibrosis that abuts the spinal tissue, canal, and other surrounding areas.
59 Citations
16 Claims
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1. A method for repairing an intervertebral disc comprising:
- forming a hole in an annulus fibrosis;
removing damaged annulus fibrosis or nucleus pulposus material from an intervertebral disc space of an intervertebral disc;
inserting an interbody fusion implant that does not contain an osteogenic inhibitory agent into the intervertebral disk space; and
closing the hole formed in the annulus fibrosis at least in part by delivering a growth-inhibiting matrix in or about the hole, the growth-inhibiting matrix adapted to prevent tissue or growth agents associated with the implant from migrating into areas outside the intervertebral disk space, and the growth-inhibiting matrix does not contain growth agents and comprises a bio-active additive that is present in an amount of about 1% to 10% of the total growth-inhibiting matrix volume. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
- forming a hole in an annulus fibrosis;
Specification