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Sample metering device and assay device with integrated sample dilution

  • US 9,034,634 B2
  • Filed: 12/01/2011
  • Issued: 05/19/2015
  • Est. Priority Date: 12/03/2010
  • Status: Active Grant
First Claim
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1. A sensor cartridge for sensing at least one analyte in a sample, comprising:

  • at least one sensor;

    a sample chamber between a sample entry port and a sample isolation unit and including a diluent introduction port therebetween for introducing diluent into said sample chamber, wherein a region of the sample chamber between said dilution introduction port and said sample isolation unit defines a dilution chamber and a metered volume of sample for dilution;

    a diluent package containing a diluent;

    a diluent conduit configured for transporting diluent from the diluent package to the diluent introduction port;

    a pump configured to transfer said diluent through the diluent conduit and the diluent introduction port, and into said dilution chamber to form a diluted sample, and further configured to transport the diluted sample to the at least one sensor; and

    a pump conduit beginning at the pump and ending at an air introduction port on the diluent conduit.

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