Imaging device and method

• US 9,037,220 B2
• Filed: 05/12/2006
• Issued: 05/19/2015
• Est. Priority Date: 05/16/2005
• Status: Active Grant

• Current Assignee: University of Leicester
• Original Assignee: University of Leicester
• Inventors: Lees, John Ernest Wyper, Perkins, Alan Christopher
• Primary Examiner(s): CHAO, ELMER M
• Application Number:
  US11/913,892
• Publication Number:
  US 20080242980A1
• Time in Patent Office: 3,294 Days
• Field of Search: 600/436, 600/431, 600/113, 600/129, 600/181, 600/182, 600/160, 600/109, 600/178, 600/117, 600/118, 600/473, 600/476, 348/162, 348/65
• US Class Current: 600/436
• CPC Class Codes: A61B 6/4258 for detecting non x-ray radiation, e.g. gamma radiation A61B6/037 takes precedence
• CPC Class Codes: G01T 1/161 Applications in the field of nuclear medicine, e.g. in vivo counting apparatus for radiation diagnosis A61B6/00

Abstract

A device (1) for use in imaging a subject using both light and gamma rays emanating from the subject, the device including: a first sensor means (2) responsive to light received thereby from the subject to generate first signals (6) for use in forming a first image (10) of the subject; a second sensor means (3) responsive to gamma rays received thereby from the subject to generate second signals (7) for use in forming a second image (11) of the subject and arranged to receive gamma rays from the subject which have passed from the subject through the first sensor means before reaching the second sensor means.

Claims

1. A device for use in imaging a subject using both light from a subject and gamma rays emanating from a radioactive substance within the subject, the device including:

a first sensor which includes a solid state pixel device responsive to light received thereby from the subject to generate first signals for use in forming a first image of the subject; and

a second sensor responsive to gamma rays received thereby from the subject to generate second signals for use in forming a second image of the subject and arranged to receive gamma rays from the subject which have passed from the subject through the first sensor before reaching the second sensor.

2. A device according to claim 1 wherein the first sensor is dimensioned and arranged to impart substantially no attenuation of gamma rays which are incident thereupon from the subject and propagating towards the second sensor in the field of vision thereof.

3. A device according to claim 1 in which the first sensor and the second sensor are arranged to receive light and gamma rays, respectively, which propagate from the subject upon substantially coincident paths such that the first sensor has a field of vision at least a part of which corresponds with at least a part of the field of vision of the second sensor.

4. A device according to claim 1 in which both the first sensor and the second sensor have a field of vision wherein the second sensor and the first sensor are co-aligned so as to share substantially a common field of vision.

5. A device according to claim 1 in which the second sensor has a field of vision and an aperture delimiting the field of vision thereof, and the first sensor substantially covers the whole of the aperture.

6. A device according to claim 1 in which the first sensor is attached to the second sensor.

7. A device according to claim 1 including a collimation device arranged between the first sensor and the second sensor to collimate gamma rays which have passed from the subject through the first sensor before reaching the second sensor.

8. A device according to claim 1 in which the second sensor includes a solid-state pixel sensor device having pixel sensors responsive to the direct receipt of gamma rays to produce said second signals.

9. A device according to claim 1 in which the second sensor includes a scintillator device responsive to gamma rays from the object by scintillation, and a scintillation sensor arranged to generate said second signals in response to said scintillation.

10. A device according to claim 9 in which the second sensor includes a collimation device arranged between the first sensor and the scintillator device of the second sensor to collimate gamma rays which have passed from the subject through the first sensor before reaching the scintillation sensor of the second sensor.

11. A device according to claim 1 including a control that controls the first and second sensor to simultaneously generate respective first and second signals in response to concurrent light and gamma rays from said subject, and a signal processing device to generate image data from the concurrent first and second data signals representing an image composite of both the image of the subject according to light and concurrently according to gamma radiation.

12. A device according to claim 1 in which the second sensor includes a solid-state pixel sensor array, and a processing device arranged to receive an input from the pixel sensor array being configurable to operate in a photon counting mode to generate said second signal according to said input.

13. A stereoscope for use in imaging a subject stereoscopically including:

a first device according to claim 1 for imaging the subject;

a second device according to claim 1 for imaging the subject concurrently with the first device being separate from the first device and arranged such that the field of vision of the second sensor of the second device differs from the concurrent field of vision of the second sensor of the first device by a finite predetermined parallax;

signal processing device to generate image data from the concurrent first and second signals of both the first and second device representing a three-dimensional (3D) stereoscopic composite view of the image of the subject both according to light and concurrently according to gamma radiation.

14. A method of imaging a subject using both light from the subject and gamma rays emanating from a radioactive substance within the subject, the method including:

detecting light from the subject with a first sensor and therewith generating first signals for use in forming a first image of the subject; and

detecting with a second sensor gamma rays from the subject which have passed from the subject through the first sensor before reaching the second sensor and therewith generating second signals for use in forming an image second image of the subject.

15. A method according to claim 14 including arranging the first sensor and the second sensor to receive light and gamma rays, respectively, which propagate from the subject concurrently upon substantially coincident paths such that the first sensor has a field of vision at least a part of which corresponds with at least a part of the field of vision of the second sensor.

16. A method according to claim 14 including co-aligning the first and second sensor so as to share substantially a common field of vision.

17. A method according to claim 14 including providing the second sensor with an aperture delimiting the field of vision thereof, and substantially covering the whole of the aperture with the first sensor.

18. A method according to claim 14 in which the first sensor is attached to the second sensor.

19. A method according to claim 14 including detecting said gamma rays with the second sensor by generating said second signals in response to the direct receipt of gamma rays by solid-state pixel sensors of the second sensor.

20. A method according to claim 14 including detecting said gamma rays with said second sensor by detecting scintillations within a scintillator device thereof responsive to gamma rays from the object by scintillation, and generating said second signals in response to said scintillation.

21. A method according to claim 14 including collimating gamma rays which have passed from the subject through the first sensor before being detected by the second sensor.

22. A method according to claim 14 including controlling the first and second sensor to generate respective first and second signals in response to light and gamma rays from said subject, and generating image data from the first and second data signals representing an image composite of the image of the subject both according to light and concurrently according to gamma radiation.

23. A method of imaging a subject stereoscopically including:

in a first step generating said first and second signals according to the method of claim 14 for imaging the subject;

in a second step generating said first and second signals according to the method of claim 14 for imaging the subject such that the field of vision of the image associated with of the second step differs from the field of vision of the image associated with the first step by a finite predetermined parallax; and

generating image data from the first and second signals generated in both the first and second steps representing a three-dimensional (3D) stereoscopic composite view of the image of the subject both according to light and concurrently according to gamma radiation.