Biological sample measuring device

• US 9,039,974 B2
• Filed: 01/16/2012
• Issued: 05/26/2015
• Est. Priority Date: 02/02/2011
• Status: Active Grant

• Current Assignee: PHC Holdings Corporation
• Original Assignee: Panasonic Healthcare Holdings Co., Ltd.
• Inventors: Hironaka, Shouko, Shinno, Teppei, Yoshioka, Eriko, Miki, Takashi
• Primary Examiner(s): Hyun, Paul
• Assistant Examiner(s): Eom, Robert
• Application Number:
  US13/993,171
• Publication Number:
  US 20130266482A1
• Time in Patent Office: 1,226 Days
• Field of Search: 205 77-794555, 422 50- 98, 436 8- 19, 436 86- 99
• US Class Current: 422/82.02
• CPC Class Codes: G01N 27/3271 Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood amperometry per se G01N27/49; aspects concerning the enzyme reagent C12Q1/001
• CPC Class Codes: G01N 27/3273 Devices therefor, e.g. test element readers, circuitry details not specific to biochemical electrodes G01N33/4875
• CPC Class Codes: G01N 33/66 involving blood sugars, e.g. galactose

Abstract

A biological sample measuring device including a mounting portion to which a biological sample measuring sensor is mounted, a voltage application section that applies voltage to a counter electrode of the biological sample measuring sensor mounted to the mounting portion, amplifiers that are selectively connected to a working electrode of the biological sample measuring sensor, and a determination section that is connected to these amplifiers. The determination section has a threshold determination section that determines a voltage value obtained by voltage conversion of the current value of the working electrode, a same determination section that selectively connects the amplifiers to the working electrode depending on the determination of the threshold determination section, and identifies the sample deposited on the biological sample measuring sensor from the output of the selected amplifier, and an output section that outputs a measurement value corresponding to the identified sample.

Claims

1. A biological sample measuring device, comprising:

a mounting portion to which is mounted a biological sample measuring sensor, said biological sample measuring sensor having an electrode section including at least a working electrode and a counter electrode, and a reagent provided on the electrode section, wherein a biological sample is deposited on the biological sample measuring sensor and reacts with the reagent;

a voltage application section that applies voltage to the electrode section of the biological sample measuring sensor mounted to the mounting portion;

a current-voltage converter connected to the working electrode of the biological sample measuring sensor;

a first amplifier connected to the current-voltage converter, the first amplifier being configured to amplify a signal outputted from the working electrode, and amplify the signal at a first amplitude;

a second amplifier connected to the current-voltage converter, the second amplifier being configured to amplify a signal outputted from the working electrode, and amplify the signal at a second amplitude that is greater than the first amplitude; and

a controller that compares the value of an output result outputted from either the first amplifier or the second amplifier with a preset threshold, and selectively uses either the first amplifier or the second amplifier.

2. The biological sample measuring device according to claim 1,

wherein the controller determines the type of biological sample on the basis of the output result outputted from either the first amplifier or the second amplifier.

3. The biological sample measuring device according to claim 2,

wherein the controller detects the slope of the output result in a specific time band, and determines whether the biological sample deposited on the biological sample measuring sensor is a blood sample or a control liquid.

4. The biological sample measuring device according to claim 1,

wherein the controller measures the concentration of the biological sample on the basis of the output result outputted from the first amplifier or the second amplifier.

5. The biological sample measuring device according to claim 4,

wherein the controller selects between the first and second amplifiers by comparing the threshold with an output result of a voltage pattern used for biological sample detection and applied prior to measurement of the concentration of the biological sample.

6. A biological sample measuring device, comprising:

a mounting portion to which is mounted a biological sample measuring sensor, said biological sample measuring sensor having an electrode section including at least a working electrode and a counter electrode, and a reagent provided on the electrode section, wherein a biological sample is deposited on the biological sample measuring sensor and reacts with the reagent;

a voltage application section that applies voltage to the electrode section of the biological sample measuring sensor mounted to the mounting portion;

a current-voltage converter connected to the working electrode of the biological sample measuring sensor;

a first amplifier connected to the current-voltage converter, the first amplifier being configured to amplify a signal outputted from the working electrode, and amplify the signal at a first amplitude;

a second amplifier connected to the current-voltage converter, the second amplifier being configured to amplify a signal outputted from the working electrode, and amplify the signal at a second amplitude that is greater than the first amplitude;

a first switch provided at the first amplifier and a second switch provided at the second amplifier such that one of the first amplifier and the second amplifier is prevented from outputting while the other one of the first amplifier and the second amplifier is outputting; and

a controller that compares the value of an output result outputted from either the first amplifier or the second amplifier with a preset threshold, and controls the switch so as to activate either one of the first amplifier or the second amplifier.