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Diagnostic kit and methods for radioimaging myocardial perfusion

  • US 9,040,016 B2
  • Filed: 07/19/2007
  • Issued: 05/26/2015
  • Est. Priority Date: 01/13/2004
  • Status: Active Grant
First Claim
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1. A method of radioimaging a myocardial perfusion while avoiding at least some liver radioactivity, the method comprising in sequence the steps of:

  • (a) administering to a subject a first dose of a first radiopharmaceutical;

    (b) subjecting said subject to a physical stress;

    (c) administering to said subject at a peak of said physical stress a second dose of a second radiopharmaceutical, said second dose being higher than said first dose; and

    (d) immediately, within a time interval of less than 3 minutes from said administering in step (c), radioimaging a heart of said subject with a radioimaging camera using a 3D non-coincidence imaging method, wherein said first radiopharmaceutical comprises an isotope including Tl-201 or Tc-99m and said second radiopharmaceutical comprises an isotope including Tc-99m or Iodine-123, thereby radioimaging a myocardial perfusion.

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