Diagnostic kit and methods for radioimaging myocardial perfusion
First Claim
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1. A method of radioimaging a myocardial perfusion while avoiding at least some liver radioactivity, the method comprising in sequence the steps of:
- (a) administering to a subject a first dose of a first radiopharmaceutical;
(b) subjecting said subject to a physical stress;
(c) administering to said subject at a peak of said physical stress a second dose of a second radiopharmaceutical, said second dose being higher than said first dose; and
(d) immediately, within a time interval of less than 3 minutes from said administering in step (c), radioimaging a heart of said subject with a radioimaging camera using a 3D non-coincidence imaging method, wherein said first radiopharmaceutical comprises an isotope including Tl-201 or Tc-99m and said second radiopharmaceutical comprises an isotope including Tc-99m or Iodine-123, thereby radioimaging a myocardial perfusion.
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Abstract
A method of radioimaging a myocardial perfusion, the method including in sequence:
- administering to a subject a low dose of a first radiopharmaceutical;
- subjecting the subject to a physical stress;
- administering to the subject at a peak of said physical stress a medium or high dose of a second radiopharmaceutical; and
- immediately radioimaging using a 3D non-coincidence imaging method a heart of the subject, thereby radioimaging a myocardial perfusion.
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10 Claims
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1. A method of radioimaging a myocardial perfusion while avoiding at least some liver radioactivity, the method comprising in sequence the steps of:
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(a) administering to a subject a first dose of a first radiopharmaceutical; (b) subjecting said subject to a physical stress; (c) administering to said subject at a peak of said physical stress a second dose of a second radiopharmaceutical, said second dose being higher than said first dose; and (d) immediately, within a time interval of less than 3 minutes from said administering in step (c), radioimaging a heart of said subject with a radioimaging camera using a 3D non-coincidence imaging method, wherein said first radiopharmaceutical comprises an isotope including Tl-201 or Tc-99m and said second radiopharmaceutical comprises an isotope including Tc-99m or Iodine-123, thereby radioimaging a myocardial perfusion. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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Specification