Treatment of pain using placental stem cells
First Claim
1. A method of treating neuropathic pain in an individual, comprising administering to the individual a therapeutically effective amount of placental stem cells, wherein (i) said placental stem cells express one or more genes at a detectably higher level than an equivalent number of bone marrow-derived mesenchymal stem cells (BM-MSCs), wherein said one or more genes are ELOVL2, ST3GAL6, ST6GALNAC5, and/or SLC12A8, (ii) the therapeutically effective amount is an amount sufficient to cause a detectable improvement in said neuropathic pain, and (iii) said neuropathic pain is caused by a drug, wherein said drug is or comprises a platinum-containing anticancer drug or paclitaxel.
3 Assignments
0 Petitions
Accused Products
Abstract
Provided herein are methods of treatment of an individual having pain, e.g., neuropathic pain, comprising administering to the individual a therapeutically effective amount of tissue culture plastic adherent placental stem cells (PDAC™).
-
Citations
18 Claims
- 1. A method of treating neuropathic pain in an individual, comprising administering to the individual a therapeutically effective amount of placental stem cells, wherein (i) said placental stem cells express one or more genes at a detectably higher level than an equivalent number of bone marrow-derived mesenchymal stem cells (BM-MSCs), wherein said one or more genes are ELOVL2, ST3GAL6, ST6GALNAC5, and/or SLC12A8, (ii) the therapeutically effective amount is an amount sufficient to cause a detectable improvement in said neuropathic pain, and (iii) said neuropathic pain is caused by a drug, wherein said drug is or comprises a platinum-containing anticancer drug or paclitaxel.
Specification