Closed-loop vagus nerve stimulation
First Claim
1. A system for vagus nerve stimulation of a patient, the system comprising:
- an accelerometer configured to provide patient motion signals;
an input assembly adapted to receive the patient motion signals, the input assembly including an acceleration-based disease state estimator configured to primarily use the patient motion signals to generate a disease state estimate of the patient, the input assembly further adapted to process the patient motion signals to generate one or more control input signals;
an output assembly adapted to receive the one or more control input signals from the input assembly and generate a neuromodulation signal based at least in part on a comparison of the disease state estimate and a reference input corresponding to a target disease state; and
an electrode configured to deliver the neuromodulation signal to the patient'"'"'s vagus nerve.
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Accused Products
Abstract
The present invention provides a closed-loop system for treating neurological disorders, such as epilepsy. In one embodiment the system comprises an input assembly that is adapted to receive one or more signals from a patient that are indicative of a patient'"'"'s neurological state. The input assembly processes the one or more signals to generate one or more control input signals. An output assembly receives the one or more control input signals from the input assembly and generate a neuromodulation signal that is a function of the patient'"'"'s neurological state. An electrode array is configured to deliver the neuromodulation signal to a patient'"'"'s peripheral nerve, such as the vagus nerve.
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Citations
17 Claims
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1. A system for vagus nerve stimulation of a patient, the system comprising:
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an accelerometer configured to provide patient motion signals; an input assembly adapted to receive the patient motion signals, the input assembly including an acceleration-based disease state estimator configured to primarily use the patient motion signals to generate a disease state estimate of the patient, the input assembly further adapted to process the patient motion signals to generate one or more control input signals; an output assembly adapted to receive the one or more control input signals from the input assembly and generate a neuromodulation signal based at least in part on a comparison of the disease state estimate and a reference input corresponding to a target disease state; and an electrode configured to deliver the neuromodulation signal to the patient'"'"'s vagus nerve. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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Specification