Transcutaneous analyte sensor
First Claim
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1. A device for measurement of an analyte concentration in a host, the device comprising:
- a sensor comprising a first electrode and a second electrode coaxially located with the first electrode, wherein the sensor comprises an in vivo portion configured for insertion into a host and an ex vivo portion configured for electrical connection to sensor electronics located outside of the host, wherein the ex vivo portion comprises a first electrical connection area associated with the first electrode and a second electrical connection area associated with the second electrode;
a membrane system disposed on an electroactive portion of the first electrode; and
a contact subassembly configured to electrically connect the sensor with sensor electronics, wherein a first electrically conductive portion of the contact subassembly circumscribes at least a portion of a periphery of the first electrical connection area, and wherein a second electrically conductive portion of the contact subassembly circumscribes at least a portion of a periphery of the second electrical connection area.
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Abstract
The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
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Citations
33 Claims
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1. A device for measurement of an analyte concentration in a host, the device comprising:
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a sensor comprising a first electrode and a second electrode coaxially located with the first electrode, wherein the sensor comprises an in vivo portion configured for insertion into a host and an ex vivo portion configured for electrical connection to sensor electronics located outside of the host, wherein the ex vivo portion comprises a first electrical connection area associated with the first electrode and a second electrical connection area associated with the second electrode; a membrane system disposed on an electroactive portion of the first electrode; and a contact subassembly configured to electrically connect the sensor with sensor electronics, wherein a first electrically conductive portion of the contact subassembly circumscribes at least a portion of a periphery of the first electrical connection area, and wherein a second electrically conductive portion of the contact subassembly circumscribes at least a portion of a periphery of the second electrical connection area. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29)
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30. A sensor for measurement of a glucose concentration in a host, the sensor comprising:
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a first wire comprising a metallic rod coated with an insulating material; first and second electrodes located on an outer surface of the insulating material; and a membrane system disposed on an electroactive portion of the first electrode, wherein the membrane system comprises a permeability ratio of oxygen-to-glucose of at least about 50;
1, wherein the electroactive portion of the first electrode has a surface area of from about 0.000084 cm2 to about 0.016 cm2, and wherein the sensor is configured to generate less than about 100 picoAmps of current per 1 mg/dL of glucose concentration. - View Dependent Claims (31, 32, 33)
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Specification