Systems and methods for providing a distributed virtual stimulation cathode for use with an implantable neurostimulation system

• US 9,044,610 B2
• Filed: 03/25/2013
• Issued: 06/02/2015
• Est. Priority Date: 03/15/2013
• Status: Active Grant

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Inventors: Rosenberg, Stuart, Cholette, Martin, Min, Xiaoyi
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): GHAND, JENNIFER LEIGH-STEWAR
• Application Number:
  US13/850,088
• Publication Number:
  US 20140277259A1
• Time in Patent Office: 799 Days
• Field of Search: 607/46
• US Class Current: 1/1
• CPC Class Codes: A61N 1/0553 Paddle shaped electrodes, e.g. for laminotomy
• CPC Class Codes: A61N 1/36071 Pain

Abstract

Techniques are provided for controlling and delivering spinal cord stimulation (SCS) or other forms of neurostimulation. In one example, neurostimulation pulses are generated wherein successive pulses alternate in polarity so that a pair of electrodes alternate as cathodes. Each pulse has a cathodic amplitude sufficient to achieve cathodic capture of tissues adjacent the particular electrode used as the cathode for the pulse. The neurostimulation pulses are delivered to patient tissues using the electrodes to alternatingly capture tissues adjacent opposing electrodes via cathodic capture to achieve a distributed virtual stimulation cathode. Various pulse energy savings techniques are also set forth that exploit the distributed virtual stimulation cathode.

Claims

1. A method for use with an implantable neurostimulation system for implant within a patient wherein the system includes at least two electrodes, the method comprising:

generating neurostimulation pulses wherein successive pulses alternate in polarity so that at least two opposing electrodes alternate as cathodes and wherein each pulse, from the successive pulses, has a cathodic amplitude sufficient to achieve cathodic capture of tissues adjacent a particular electrode of the at least two opposing electrodes used as the cathode for the pulse; and

delivering the neurostimulation pulses to patient tissues using the at least two electrodes to alternatingly capture tissues adjacent the at least two opposing electrodes via cathodic capture to achieve a distributed virtual stimulation cathode.

2. The method of claim 1 wherein the neurostimulation pulses are each biphasic and wherein a cathodic phase of a first biphasic pulse of a pair of successive pulses achieves capture of tissues adjacent a first electrode of the at least two opposing electrodes and wherein a cathodic phase of a second biphasic pulse of the pair of pulses achieves capture of tissues adjacent a second electrode of the at least two opposing electrodes.

3. The method of claim 2 wherein a recharge phase of the first biphasic pulse is configured to precondition nerve cells adjacent a respective electrode of the at least two opposing electrodes to achieve a lower stimulation threshold for the second biphasic pulse.

4. The method of claim 2 wherein a capacitor employed to provide pulse energy is only partially discharged during the cathodic phase of the first biphasic pulse to retain energy to provide stimulation energy for the first phase of the second biphasic pulse.

5. The method of claim 1 wherein the neurostimulation pulses are each monophasic and wherein a first monophasic pulse of a pair of successive pulses achieves cathodic capture of tissues adjacent a first electrode of the at least two opposing electrodes and a second monophasic pulse of the pair of pulses achieves cathodic capture of tissues adjacent a second electrode of the at least two opposing electrodes.

6. The method of claim 1 wherein the implantable neurostimulation system operates in conjunction with an external programmer equipped to program the implantable system using one or more simulation sets specifying an electrode configuration to be used to deliver stimulation and wherein a single stimulation set is used to program the implantable neurostimulation system to alternatingly capture tissues adjacent the different electrodes of the at least two opposing electrodes via distributed virtual cathodic stimulation.

7. The method of claim 6 wherein each stimulation set specifies a set of neurostimulation control parameters including one or more of:

a neuromodulation amplitude;

a neuromodulation frequency;

a neuromodulation pulse width; and

a neuromodulation electrode configuration.

8. The method of claim 1 wherein the successive pulses are configured to substantially achieve charge balance.

9. The method of claim 1 wherein implantable neurostimulation system includes a spinal cord stimulation (SCS) device.

10. The method of claim 1 wherein the at least two opposing electrodes include a pair of electrodes that alternate as cathodes between first, second and third successive pulses.

11. The method of claim 1 wherein the generating operation includes partially discharging a capacitor during a first pulse of a pair of successive pulses to achieve capture of tissues adjacent a first electrode of the at least two opposing electrodes and partially discharging the capacitor during a second first pulse of the pair of successive pulses to achieve capture of tissues adjacent a second electrode of the at least two opposing electrodes.

12. The method of claim 1, wherein the successive pulses include first and second pulses that achieve two sites of cathodal stimulation with a single stimulation set formed by the at least two opposing electrodes.

13. A system for use with an implantable neurostimulation system for implant within a patient wherein the system includes at least two electrodes, the system comprising:

a neurostimulation pulse generator operative to generate neurostimulation pulses wherein successive pulses alternate in polarity so that at least two opposing electrodes alternate as cathodes and wherein each pulse, from the successive pulses, has a cathodic amplitude sufficient to achieve cathodic capture of tissues adjacent a particular electrode of the at least two opposing electrodes used as the cathode for the pulse; and

a neurostimulation pulse delivery system operative to deliver the neurostimulation pulses to patient to alternatingly capture tissues adjacent the at least two opposing electrodes via cathodic capture to achieve a distributed virtual stimulation cathode.

14. The system of claim 13 wherein the neurostimulation pulse delivery system includes one or more leads.

15. The system of claim 14 wherein at least one lead is one or more of:

a percutaneous lead;

a percutaneous lead with five columns of electrodes, a paddle lead and a segmented electrode lead.

16. The system of claim 13 wherein implantable neurostimulation system includes a spinal cord stimulation (SCS) device.

17. The system of claim 13 wherein the at least two opposing electrodes include a pair of electrodes that alternate as cathodes between first, second and third successive pulses.

18. The system of claim 13 further comprising a capacitor, wherein the generator discharges the capacitor during a first pulse of a pair of successive pulses to achieve capture of tissues adjacent a first electrode of the at least two opposing electrodes and partially discharges the capacitor during a second first pulse of the pair of successive pulses to achieve capture of tissues adjacent a second electrode of the at least two opposing electrodes.

19. The system of claim 13 wherein the successive pulses include first and second pulses that achieve two sites of cathodal stimulation with a single stimulation set formed by the at least two opposing electrode.

20. An external system for use with an implantable neurostimulation system for implant within a patient wherein the implantable neurostimulation system includes at least two electrodes, the external system comprising:

a distributed virtual cathodic stimulation-based programming system operative to generate a stimulation set for programming the implantable neurostimulation system to provide distributed virtual cathodic stimulation; and

a telemetry system operative to control transmission of stimulation set programming commands to the implantable neurostimulation system for controlling the implantable neurostimulation system, wherein the distributed virtual cathodic stimulation is formed by generating neurostimulation pulses wherein successive pulses alternate in polarity so that at least two opposing electrodes alternate as cathodes and wherein each pulse, from the successive pulses, has a cathodic amplitude sufficient to achieve cathodic capture of tissues adjacent a particular electrode of the at least two opposing electrodes used as the cathode for the pulse.