System and method for transferring and/or working near a radioactive payload using shield-gate apparatus

• US 9,047,996 B2
• Filed: 11/06/2014
• Issued: 06/02/2015
• Est. Priority Date: 05/19/2011
• Status: Active Grant

• Current Assignee: Holtec International, Inc.
• Original Assignee: Holtec International, Inc.
• Inventors: Agace, Stephen J.
• Primary Examiner(s): Johnston, Phillip A
• Application Number:
  US14/534,456
• Publication Number:
  US 20150060705A1
• Time in Patent Office: 208 Days
• Field of Search: 250/507.1
• US Class Current: 1/1
• CPC Class Codes: A61K 2039/507 Comprising a combination of two or more separate antibodies
• CPC Class Codes: A61K 2039/545 characterised by the dose, timing or administration schedule
• CPC Class Codes: A61K 38/18 Growth factors; Growth regulators
• CPC Class Codes: A61K 38/195 Chemokines, e.g. RANTES
• CPC Class Codes: A61K 38/36 Blood coagulation or fibrinolysis factors
• CPC Class Codes: A61K 39/3955 against proteinaceous materials, e.g. enzymes, hormones, lymphokines
• CPC Class Codes: A61K 45/06 Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• CPC Class Codes: A61K 9/0019 Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner non-active ingredients are additionally classified in A61K47/00
• CPC Class Codes: A61P 35/00 Antineoplastic agents
• CPC Class Codes: C07K 14/475 Growth factors; Growth regulators
• CPC Class Codes: C07K 14/522 Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4, KC
• CPC Class Codes: C07K 14/755 Factors VIII , e.g. factor VIII C (AHF), factor VIII Ag (VWF)
• CPC Class Codes: C07K 16/2818 against CD28 or CD152
• CPC Class Codes: C07K 16/2827 against B7 molecules, e.g. CD80, CD86
• CPC Class Codes: C07K 16/2878 against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
• CPC Class Codes: C07K 2317/24 containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
• CPC Class Codes: C07K 2317/75 Agonist effect on antigen
• CPC Class Codes: C07K 2317/92 Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
• CPC Class Codes: C07K 2319/30 Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
• CPC Class Codes: C07K 2319/70 containing domain for protein-protein interaction
• CPC Class Codes: G21F 5/12 : Closures for containers; Sealing arrangements
• CPC Class Codes: G21F 5/14 : Devices for handling containers or shipping-casks, e.g. transporting devices loading and unloading, filling of containers cranes, load-engaging elements or devices for cranes, capstans, winches or tackles B66C
• CPC Class Codes: G21F 7/005 : Shielded passages through walls; Locks; Transferring devices between rooms between glove-boxes G21F7/047

Abstract

A method of transferring a radioactive payload and a method of performing work within a cavity of a shielding container. In one embodiment, the invention is a method comprising a) positioning a shield-gate apparatus atop a first shielding container, the shield-gate apparatus comprising a body, a passageway extending through the body, and one or more movable shielding gates that are open; and b) lifting a removable shielding lid of the first shielding container through the passageway, wherein during closing of the one or more shielding gates the removable shielding lid is maintained in a position in which either: (1) a bottom surface of the removable shielding lid is disposed within the passageway at a height above the one or more shielding gates; or (2) the bottom surface of the removable shielding lid is substantially flush with the top surface of the body of the shield-gate apparatus.

Claims

1. A method of transferring a radioactive payload from a first shielding container to a second shielding container comprising:

a) positioning a shield-gate apparatus atop the first shielding container, the shield-gate apparatus comprising a body, a passageway extending along an axis through the body from a first opening in a top surface of the body to a second opening in a bottom surface of the body, and one or more movable shielding gates;

b) opening the one or more shielding gates of the shield-gate apparatus;

c) lifting a removable shielding lid of the first shielding container through the passageway until the removable shielding lid is above the one or more shielding gates and closing the one or more shielding gates of the shield-gate apparatus;

d) positioning a shielding block atop the shield-gate structure to enclose the first opening, the shielding block comprising a central axis and a first tool port offset from the central axis of the shielding block;

e) removing a first shielding plug from the first tool port and opening the one or more shielding gates of the shield-gate apparatus;

f) rotating the shielding block about the central axis of the shielding block to a first rotational position;

g) inserting a first tool through the first tool port and removing one of a plurality of fasteners that secure a removable pressure vessel lid to a pressure vessel body using the first tool, the radioactive payload positioned within the pressure vessel;

h) rotating the shielding block about the central axis from the first rotational position to a second rotational position;

i) removing another one of the plurality of fasteners using the first tool;

j) removing a second radiation shielding plug from a second tool port of the shielding block that is aligned with the central axis of the shielding block;

k) inserting a second tool through the second tool port and lifting the pressure vessel lid through the passageway using the second tool until the pressure vessel lid contacts the shielding block;

l) lifting both the shielding block and the removable pressure vessel lid using the second tool until the removable pressure vessel lid is above the one or more gates of the shield-gate apparatus and closing the one or more shielding gates of the shield-gate apparatus;

m) positioning a second shielding container atop the shield-gate apparatus and opening the one or more shielding gates of the shield-gate apparatus; and

n) lifting the radioactive payload through the passageway and into a second cavity of the second shielding container.

2. The method of claim 1 wherein the one or more shielding gates are movable between:

(1) a closed state in which the one or more shielding gates block the passageway; and

(2) an open state in which the one or more shielding gates do not obstruct the passageway.

3. The method of claim 1 wherein the removable shielding lid has a bottom portion having a transverse cross-section that substantially corresponds to a transverse cross-section of the first opening in the top surface of the body of the shield-gate apparatus in both size and shape, and wherein step c) further comprises maintaining the removable shielding lid in a position in which either:

(1) a bottom surface of the removable shielding lid is disposed within the passageway at a height above the one or more shielding gates;

or (2) the bottom surface of the removable shielding lid is substantially flush with the top surface of the body of the shield-gate apparatus, during the closing of the one or more shielding gates.

4. The method of claim 1 wherein the removable pressure vessel lid has a bottom portion having a transverse cross-section that substantially corresponds to a transverse cross-section of the first opening in the top surface of the body of the shield-gate apparatus in both size and shape, and wherein step l) further comprises maintaining the shielding block and the removable pressure vessel lid in a position in which either:

(1) a bottom surface of the removable pressure vessel lid is disposed within the passageway at a height above the one or more shielding gates;

or (2) the bottom surface of the removable pressure vessel lid is substantially flush with the top surface of the body of the shield-gate apparatus, during the closing of the one or more shielding gates.

5. The method of claim 1 wherein in the first rotational position, a first port axis of the first tool port is substantially coaxial with a first fastener axis of the one of the plurality of fasteners, and wherein in the second rotational position, the first port axis of the first tool port is substantially coaxial with a second fastener axis of the another one of the plurality of fasteners.

6. The method of claim 1 wherein the shield-gate apparatus further comprises a retaining feature, and wherein step d) further comprises positioning the shielding block atop the shield-gate structure so that the retaining feature prevents relative transverse movement between the shielding block and the shield-gate apparatus while allowing relative rotation between the shielding block and the shield-gate apparatus about the central axis of the shielding block.

7. The method of claim 6 wherein the second shielding container comprises a shield-gate and a structure protruding from a bottom surface of the shield-gate, and wherein step m) further comprises positioning the second shielding container atop the shield-gate apparatus so that interaction between the structure and the retaining feature of the shield-gate apparatus prevents relative transverse movement between the second shielding container and the shield-gate apparatus.

8. A method of providing access to a radioactive payload located within a first cavity of a first shielding container, the method comprising:

a) positioning a shield-gate apparatus atop the first shielding container, the shield-gate apparatus comprising a body, a passageway extending along an axis through the body from a first opening in a top surface of the body to a second opening in a bottom surface of the body, and one or more movable shielding gates that are open; and

b) lifting a removable shielding lid of the first shielding container through the passageway and closing the one or more shielding gates of the shield-gate apparatus, wherein the removable shielding lid is maintained in a position in which either;

(1) a bottom surface of the removable shielding lid is disposed within the passageway at a height above the one or more shielding gates;

or (2) the bottom surface of the removable shielding lid is substantially flush with the top surface of the body of the shield-gate apparatus, during the closing of the one or more shielding gates.

9. A method of providing access to a radioactive payload located within a pressure vessel disposed within a first cavity of a first shielding container, the method comprising:

a) positioning a shield-gate apparatus atop the first shielding container, the shield-gate apparatus comprising a body, a passageway extending along an axis through the body from a first opening in a top surface of the body to a second opening in a bottom surface of the body, and one or more movable shielding gates that are open;

b) positioning a shielding block atop the shield-gate apparatus to enclose the first opening;

c) inserting a tool through a tool port in the shielding block and engaging with the tool a removable pressure vessel lid that has been unfastened from a pressure vessel body;

d) lifting the removable pressure vessel lid through the passageway until the removable pressure vessel lid contacts the shielding block with the tool; and

e) lifting both the shielding block and the removable pressure vessel lid using the tool until the removable pressure vessel lid is above the one or more gates of the shield-gate apparatus and closing the one or more shielding gates of the shield-gate apparatus.

10. The method of claim 9 wherein step e) further comprises maintaining the shielding block and the removable pressure vessel lid in a position in which either:

(1) a bottom surface of the removable pressure vessel lid is disposed within the passageway at a height above the one or more shielding gates;

or (2) the bottom surface of the removable pressure vessel lid is substantially flush with the top surface of the body of the shield-gate apparatus, during the closing of the one or more shielding gates.

11. The method of claim 9 wherein step c) further comprises removing a shielding plug from the tool port prior to inserting the tool through the tool port.

12. A method of working within a first cavity of a first shielding container containing a radioactive payload, the system comprising:

a) positioning a shield-gate apparatus atop the first shielding container, the shield-gate apparatus comprising a body, a passageway extending along an axis through the body from a first opening in a top surface of the body to a second opening in a bottom surface of the body, and one or more movable shielding gates that are open;

b) positioning a shielding block atop the shield-gate apparatus to enclose the first opening, the shielding block comprising a tool port that is offset from an axis of rotation of the shielding block;

c) inserting a tool through the tool port and into the first cavity;

d) rotating the shielding block relative to the first shielding container about the rotational axis from a first rotational position to a second rotational position, wherein the tool performs work at the first rotational position and at the second rotational position.

13. The method of claim 12 wherein step d) further comprises preventing relative transverse movement between the shielding block and the shield-gate apparatus during said rotation.

14. The method of claim 13 wherein relative transverse movement between the shielding block and the shield-gate apparatus during said rotation is prevented by interaction between a retaining feature of the shield-gate apparatus and the shielding block.