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Method of administration of gamma hydroxybutyrate with monocarboxylate transporters

DC
  • US 9,050,302 B2
  • Filed: 03/15/2013
  • Issued: 06/09/2015
  • Est. Priority Date: 03/01/2013
  • Status: Active Grant
First Claim
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1. A method for the treatment of cataplexy in narcolepsy or excessive daytime sleepiness in narcolepsy in a patient who is currently taking gamma-hydroxybutyrate (GHB) or a salt thereof comprising:

  • administering to the patient a dose of divalproex sodium concomitant to a dose of GHB or salt thereof; and

    reducing the daily dosage amount of GHB or salt thereof administered to the patient by at least 20% wherein the daily dosage amount of GHB or salt thereof in the absence of concomitant administration of divalproex sodium is between 4.5 g to 9 g.

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