Systems and methods for mixing therapeutic agents before and/or during administration
First Claim
1. A system for mixing at least one therapeutic agent before and/or during localized delivery of the at least one therapeutic agent to treat a bodily disorder, comprising a mixing and delivery syringe, wherein the syringe comprises:
- a hollow body having a proximal end and a distal end, wherein the at least one therapeutic agent is stored;
a distal port in fluid communication with the distal end of hollow body; and
a plunger assembly comprising;
a plunging base disposed within the hollow body;
a fan disposed within the hollow body, the fan comprising rotatable blades extending radially from a rotatable central axle;
a threaded shaft comprising a distal end rotatably coupled with the rotatable central axle for enabling rotational movement of the rotatable blades about the distal end of the threaded shaft;
a threaded block in threaded communication with the threaded shaft; and
a floating motor mounted on a proximal end of the threaded shaft;
wherein,the motor is configured to rotate the threaded shaft;
the rotation of the threaded shaft in a first direction induces threaded translation of the threaded shaft through the threaded block;
the threaded translation of the threaded shaft induces axial translation of the floating motor, the fan and the plunging base towards the distal end of the hollow body; and
the axial translation of the fan induces the rotational movement of the rotatable blades about the distal end of the threaded shaft, wherein when resistance is encountered at the distal end of the hollow body, the floating motor reverses rotational direction to a second rotational direction, wherein the rotation of the threaded shaft in the second direction induces threaded translation of the threaded shaft through the threaded block and the threaded translation of the threaded shaft induxes axial translation of the floating motor, the fan and the plunging base towards the proximal end of the hollow body, wherein when resistance is encountered at the proximal end of the hollow body, the floating motor reverses rotational direction to the second rotational direction until resistance is encountered at the distal end of the hollow body.
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Accused Products
Abstract
The invention provides systems and methods for mixing of therapeutic agents before and/or during the localized application of the therapeutic agents. Most preferably, the present invention provides systems and methods for mixing of therapeutic agents before and/or during administration of the agents within a biological lumen. Various embodiments of the present invention comprise systems and methods for inducing a mixing state in the therapeutic agents, thereby inducing and/or maintaining homogeneity of the agents before and/or during localized delivery.
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Citations
13 Claims
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1. A system for mixing at least one therapeutic agent before and/or during localized delivery of the at least one therapeutic agent to treat a bodily disorder, comprising a mixing and delivery syringe, wherein the syringe comprises:
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a hollow body having a proximal end and a distal end, wherein the at least one therapeutic agent is stored; a distal port in fluid communication with the distal end of hollow body; and a plunger assembly comprising; a plunging base disposed within the hollow body; a fan disposed within the hollow body, the fan comprising rotatable blades extending radially from a rotatable central axle; a threaded shaft comprising a distal end rotatably coupled with the rotatable central axle for enabling rotational movement of the rotatable blades about the distal end of the threaded shaft; a threaded block in threaded communication with the threaded shaft; and a floating motor mounted on a proximal end of the threaded shaft; wherein, the motor is configured to rotate the threaded shaft; the rotation of the threaded shaft in a first direction induces threaded translation of the threaded shaft through the threaded block; the threaded translation of the threaded shaft induces axial translation of the floating motor, the fan and the plunging base towards the distal end of the hollow body; and the axial translation of the fan induces the rotational movement of the rotatable blades about the distal end of the threaded shaft, wherein when resistance is encountered at the distal end of the hollow body, the floating motor reverses rotational direction to a second rotational direction, wherein the rotation of the threaded shaft in the second direction induces threaded translation of the threaded shaft through the threaded block and the threaded translation of the threaded shaft induxes axial translation of the floating motor, the fan and the plunging base towards the proximal end of the hollow body, wherein when resistance is encountered at the proximal end of the hollow body, the floating motor reverses rotational direction to the second rotational direction until resistance is encountered at the distal end of the hollow body. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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Specification