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Expandable fluoropolymer device for delivery of therapeutic agents and method of making

  • US 9,050,442 B2
  • Filed: 06/22/2010
  • Issued: 06/09/2015
  • Est. Priority Date: 01/25/1999
  • Status: Expired due to Fees
First Claim
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1. A method of using a radially expandable fluid delivery device for delivery of one or more therapeutic agents, comprising:

  • locating the radially expandable fluid delivery device within a body passage in need of treatment, the radially expandable fluid delivery device formed of a radially inelastic wall having at least one microporous portion formed of a microstructure of nodes interconnected by fibrils having spaces therebetween forming generally aligned micro-channels having a porosity sufficient to cause a fluid containing the one or more therapeutic agents and supplied thereto to provide a radial deployment force to expand the fluid delivery device and to permeate through the micro-channels, the micro-channels substantially controlling the permeation of the fluid from a location interior to the wall to a location exterior to the wall by passing through the wall; and

    expanding the radially expandable fluid delivery device using a radial deployment force supplied by the fluid containing the one or more therapeutic agents in such a way that the radially expandable fluid delivery device expands and occludes the body passage and the fluid containing the one or more therapeutic agents flows from the location interior to the wall to the location exterior to the wall by flowing through the wall of the radially expandable fluid delivery device thereby delivering the one or more therapeutic agents to the body passage while also applying the radial deployment force.

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