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System and method for measuring an analyte in a sample

  • US 9,052,278 B2
  • Filed: 07/18/2011
  • Issued: 06/09/2015
  • Est. Priority Date: 07/19/2010
  • Status: Active Grant
First Claim
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1. A method of determining blood glucose concentration with a glucose measurement system that includes a test strip and test meter, the test meter having a microcontroller configured to apply a plurality of test voltages to the test strip and measure a current transient output resulting from an electrochemical reaction in a test chamber of the test strip, the method comprising:

  • inserting the test strip into a strip port connector of the test meter to connect at least two electrodes of the test strip to a strip measurement circuit;

    initiating a test sequence after deposition of a sample;

    applying a first voltage to the at least two electrodes of the test strip for a first time interval from the initiation of test sequence to cause a transformation of analytes in the sample;

    switching the first voltage to a second voltage different than the first voltage;

    changing the second voltage to a third voltage different from the first or second voltages;

    measuring a first current output of a current transient from the electrodes during an interval for the switching of the first voltage to the second voltage but prior to a complete changeover to the second voltage;

    measuring a second current output of the current transient from the electrodes after the changing from the second voltage to the third voltage;

    estimating a steady state current output of the current transient after the third voltage is maintained at the electrodes; and

    calculating a blood glucose concentration based on the first, second and steady state current output of the current transient without compensation for temperature on the glucose concentration.

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