Apparatus and method for irradiating a scattering medium with a reconstructive wave

• US 9,057,695 B2
• Filed: 09/24/2009
• Issued: 06/16/2015
• Est. Priority Date: 09/24/2009
• Status: Active Grant

• Current Assignee: Canon Kabushiki Kaisha (Canon Inc.)
• Original Assignee: Canon Kabushiki Kaisha (Canon Inc.)
• Inventors: Masumura, Takahiro
• Primary Examiner(s): KISH, JAMES M
• Application Number:
  US12/566,592
• Publication Number:
  US 20110071402A1
• Time in Patent Office: 2,091 Days
• Field of Search: 600/437, 600/473, 600/476, 359/10, 359/11, 359/22, 359/32, 356450-521, 736/03
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0097 by applying acoustic waves and detecting light, i.e. acoustooptic measurements
• CPC Class Codes: G01N 2021/1727 Magnetomodulation
• CPC Class Codes: G01N 21/1717 with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
• CPC Class Codes: G01N 21/4795 spatially resolved investigating of object in scattering medium in vivo A61B
• CPC Class Codes: G03H 1/0005 Adaptation of holography to specific applications holographic optical element G02B5/32; holographic scanner G02B26/106; recognition using holographic mask G06V10/88; holographic memories G11B7/0065, G11C13/042
• CPC Class Codes: G03H 1/02 Details of features involved during the holographic process; Replication of holograms without interference recording
• CPC Class Codes: G03H 1/04 Processes or apparatus for producing holograms G03H1/26 takes precedence
• CPC Class Codes: G03H 1/2205 using downstream optical component
• CPC Class Codes: G03H 1/2645 Multiplexing processes, e.g. aperture, shift, or wavefront multiplexing
• CPC Class Codes: G03H 1/28 superimposed holograms only
• CPC Class Codes: G03H 2001/0212 Light sources or light beam properties G03H1/06, G03H1/24 take precedence; corresponding details, see subgroups of G03H2222/00
• CPC Class Codes: G03H 2001/0467 Gated recording using pulsed or low coherence light source, e.g. light in flight, first arriving light
• CPC Class Codes: G03H 2001/2213 Diffusing screen revealing the real holobject, e.g. container filed with gel to reveal the 3D holobject
• CPC Class Codes: G03H 2001/2244 Means for detecting or recording the holobject
• CPC Class Codes: G03H 2001/2655 Time multiplexing, i.e. consecutive records wherein the period between records is pertinent per se
• CPC Class Codes: G03H 2210/62 Moving object
• CPC Class Codes: G03H 2222/10 Spectral composition
• CPC Class Codes: G03H 2260/36 Dynamic material where the lifetime of the recorded pattern is quasi instantaneous, the holobject is simultaneously reconstructed

Abstract

A system and method for irradiating a medium including irradiating the medium with an electromagnetic wave which is scattered in the medium and modulated in frequency at a position in the medium; obtaining information corresponding to an interference pattern generated by interference between the modulated electromagnetic wave and a reference wave; and generating a phase conjugate wave, based on the obtained information, which irradiates the medium.

Claims

1. An apparatus comprising:

a first irradiation unit configured to irradiate a medium with a incident wave;

a first photodetector arranged to monitor an intensity of the incident wave before being irradiated on the medium;

an ultrasound device configured to focus an ultrasound wave onto a position in the medium such that the incident wave is modulated into a frequency-shifted wave at the position where the ultrasound wave is focused by the ultrasound device;

a holographic material;

a second irradiation unit configured to irradiate the holographic material with a reference wave, a frequency difference between the reference wave and the incident wave being exactly or approximately equal to a frequency of the ultrasound wave focused by the ultrasound device, and to record information corresponding to an interference pattern formed by interference between the frequency-shifted wave and the reference wave by the holographic material;

a second photodetector configured to detect light from the holographic material while the holographic material records the information corresponding to the interference pattern;

a third irradiation unit, after the information is recorded on the holographic material, configured to irradiate the holographic material with a reading wave substantially in a direction opposite to a direction of the reference wave so that the holographic material generates a reconstructed wave to irradiate the medium to retrace trajectory of the frequency-shifted wave to the position where the ultrasound wave is focused by the ultrasound device; and

a control unit configured to control the first irradiation unit and the third irradiation unit so that an intensity of the reading wave generated from the third irradiation unit is different from an intensity of the incident wave generated from the first irradiation unit,

wherein the control unit is configured to control the first irradiation unit based on an output of the first photodetector so that the intensity of the incident wave keeps below a predetermined exposure and is configured to control the third irradiation unit so that the intensity of the reading wave is lower than the intensity of the incident wave.

2. The apparatus according to claim 1, further comprising a detection unit configured to detect a signal output from the medium in response to irradiation of the reconstructed wave.

3. The apparatus according to claim 2, wherein

the first detection unit is a third photodetector configured to detect a light signal output from the medium in response to irradiation of the reconstructed wave.

4. The apparatus according to claim 2, wherein

the first detection unit is an ultrasound detector configured to detect a photoacoustic signal output from the medium in response to irradiation of the reconstructed wave.

5. The apparatus according to claim 1, further comprising an image formation unit configured to form an image using a signal output from the medium in response to irradiation of the reconstructed wave.

6. The apparatus according to claim 1, wherein the ultrasound device is configured to detect a photoacoustic signal output from the medium in response to irradiation of the reconstructed wave.

7. The apparatus according to claim 1, wherein

the first irradiation unit and the second irradiation unit include a common electromagnetic wave source, and

the third irradiation unit includes a electromagnetic wave source different from the common electromagnetic wave source.

8. The apparatus according to claim 7, wherein

the common electromagnetic wave source is configured to generate an electromagnetic wave whose wavelength is not less than 380 nm and not more than 2500 nm.

9. The apparatus according to claim 1, wherein

the first irradiation unit, the second irradiation unit, and the third irradiation unit include a common electromagnetic wave source.

10. The apparatus according to claim 9, wherein

the common electromagnetic wave source is configured to generate an electromagnetic wave whose wavelength is not less than 380 nm and not more than 2500 nm.

11. The apparatus according to claim 1, further comprising a filter between the medium and the holographic material, wherein:

the filter reduces by a first amount an intensity of the incident wave transmitted from the medium to the holographic material;

the filter reduces by a second amount an intensity of the frequency-shifted wave transmitted from the medium to the holographic material; and

the first amount is greater than the second amount.

12. The apparatus according to claim 1, wherein the first irradiation unit includes a modulator configured to modulate a frequency of the incident wave.

13. The apparatus according to claim 1, wherein the second irradiation unit includes a modulator configured to modulate a frequency of the reference wave.

14. The apparatus according to claim 1, wherein the predetermined exposure is a maximum exposure.

15. An apparatus comprising:

an first irradiation unit configured to irradiate a medium with an incident wave;

a first photodetector arranged to monitor an intensity of the incident wave before being irradiated on the medium;

an ultrasound device configured to focus an ultrasound wave onto a position in the medium such that the incident wave is modulated into a frequency-shifted wave at the position where the ultrasound wave is focused by the ultrasound device;

a first detection unit configured to obtain information corresponding to an interference pattern generated by interference between the frequency-shifted wave and a reference wave;

a second irradiation unit configured to irradiate the first detection unit with the reference wave, a frequency difference between the reference wave and the incident wave being exactly or approximately equal to a frequency of the ultrasound wave focused by the ultrasound device;

a generation unit configured to irradiate the medium with a phase conjugation wave of the frequency-shifted wave to irradiate the medium to retrace trajectory of the frequency shifted wave to the position where the ultrasound wave is focused by the ultrasound device based on the information obtained by the first detection unit; and

a control unit configured to control the first irradiation unit and the generation unit so that an intensity of the phase conjugation wave generated from the generation unit is different from an intensity of the incident wave generated from the first irradiation unit,

wherein the control unit is configured to control the first irradiation unit based on an output of the first photodetector so that the intensity of the incident wave keep below a predetermined exposure and is configured to control the generation unit so that the intensity of the phase conjugation wave is lower than the intensity of the incident wave.

16. The apparatus according to claim 15, wherein the first detection unit comprises a CCD sensor or a CMOS sensor.

17. The apparatus according to claim 15, wherein the generation unit comprises a spatial light modulator.

18. The apparatus according to claim 15, further comprising:

a third photodetector configured to detect a light signal output from the medium in response to irradiation of the phase conjugation wave,

an ultrasound detector configured to detect a photoacoustic signal output from the medium in response to irradiation of the phase conjugation wave,

an image formation unit configured to form a first image based on the light signal detected by the third photodetector and configured to form a second image based on the photoacoustic signal detected by the ultrasound detector.

19. The apparatus according to claim 15, further comprising a second detection unit configured to detect a signal output from the medium in response to irradiation of the phase conjugation wave.

20. The apparatus according to claim 15, further comprising a third photodetector configured to detect a light signal output from the medium in response to irradiation of the phase conjugation wave.

21. The apparatus according to claim 15, further comprising an ultrasound detector configured to detect a photoacoustic signal output from the medium in response to irradiation of the phase conjugation wave.

22. The apparatus according to claim 15, wherein the ultrasound device is configured to detect a photoacoustic signal output from the medium in response to irradiation of the phase conjugation wave.

23. The apparatus according to claim 15, further comprising an image formation unit configured to form an image using a signal output from the medium in response to irradiation of the phase conjugation wave.

24. The apparatus according to claim 15, wherein the first irradiation unit and the second irradiation unit include a common electromagnetic wave source.

25. The apparatus according to claim 24, wherein the common electromagnetic wave source is configured to generate an electromagnetic wave whose wavelength is not less than 380 nm and not more than 2500 nm.

26. The apparatus according to claim 15, further comprising a filter between the medium and the first detection unit, wherein

the filter reduces by a first amount an intensity of the first electromagnetic wave transmitted from the medium to the first detection unit;

the filter reduces by a second amount an intensity of the frequency-shifted electromagnetic wave transmitted from the medium to the first detection unit; and

the first amount is greater than the second amount.

27. The apparatus according to claim 15, wherein

the first detection unit is configured to obtain the information corresponding to the interference pattern by a phase-shifting digital holography technique, the frequency difference between the reference wave and the incident wave being exactly or approximately equal to a sum of a frequency of the ultrasound wave focus by the ultrasound device and a value which is a frame rate of the first detection unit divided by a number of measurements for a phase shifting method.

28. The apparatus according to claim 15, the first irradiation unit includes a modulator configured to modulate a frequency of the incident wave.

29. The apparatus according to claim 15, wherein the second irradiation unit includes a modulator configured to modulate a frequency of the reference wave.

30. The apparatus according to claim 15, further comprising:

a third photodetector configured to detect a light signal output from the medium in response to irradiation of the phase conjugation wave and an image formation unit,

wherein the ultrasound device is configured to detect a photoacoustic signal output from the medium in response to irradiation of the phase conjugation wave,

wherein the image formation unit configured to form a first image based on the light signal detected by the third photodetector and configured to form a second image based on the photoacoustic signal detected by the ultrasound device.

31. The apparatus according to claim 15, wherein the predetermined exposure is a maximum exposure.