Compositions and methods for therapeutic delivery with frozen particles
First Claim
Patent Images
1. A therapeutic composition, comprising:
- one or more frozen particles externally coated with at least one therapeutic agent including a cytotoxic agent including a neurotoxin or neuro-muscular toxin;
one or more reinforcement agents including one or more of polyaramid, vinylester matrix, ceramic, fiberglass, broad carbide, aromatic polyamide, nylon, silk, rayon, modacrylic, olefin, polyester, aromatic polyester, vinyon, saran, spandex, vinalon, aromatic nylon, vinylidene chloride, modal, polybenzimidazole, sulfur, lyocell, orlon, zylon, polypyridobenzimidazole, vectran, acrylonitrile rubber, glass, silicon, or silica;
one or more of collagen, or elastin; and
at least one detection material.
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Abstract
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.
308 Citations
32 Claims
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1. A therapeutic composition, comprising:
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one or more frozen particles externally coated with at least one therapeutic agent including a cytotoxic agent including a neurotoxin or neuro-muscular toxin; one or more reinforcement agents including one or more of polyaramid, vinylester matrix, ceramic, fiberglass, broad carbide, aromatic polyamide, nylon, silk, rayon, modacrylic, olefin, polyester, aromatic polyester, vinyon, saran, spandex, vinalon, aromatic nylon, vinylidene chloride, modal, polybenzimidazole, sulfur, lyocell, orlon, zylon, polypyridobenzimidazole, vectran, acrylonitrile rubber, glass, silicon, or silica; one or more of collagen, or elastin; and at least one detection material. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32)
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Specification