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Implantable devices for chemonucleolysis of intervertebral discs

  • US 9,061,064 B2
  • Filed: 11/29/2006
  • Issued: 06/23/2015
  • Est. Priority Date: 08/06/2003
  • Status: Active Grant
First Claim
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1. An intervertebral disc implant comprising a chemonucleolysis agent in solid powder form, a plurality of particles and a binder, wherein the implant has a solid body throughout the cross-section of the implant and when placed into the nucleus pulposus of an intervertebral disc, the implant having a sheath comprising the chemonucleolysis agent incorporated into the sheath, the implant sustainably releases the chemonucleolysis agent into the nuclear disc tissue surrounding the implant to proteolytically degrade the tissue, the chemonucleolysis agent comprises chymopapain and is incorporated into the particles.

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