Disposable acoustic coupling medium container

• US 9,061,131 B2
• Filed: 08/17/2010
• Issued: 06/23/2015
• Est. Priority Date: 08/17/2009
• Status: Active Grant

• Current Assignee: HistoSonics, Inc, Board of Regents of the University of Michigan (University of Michigan)
• Original Assignee: HistoSonics, Inc, Board of Regents of the University of Michigan (University of Michigan)
• Inventors: Jahnke, Russell C., Bertolina, James A., Roberts, William W., Cain, Charles A., Teofilovic, Dejan, Davison, Thomas W.
• Primary Examiner(s): Le, Long V
• Assistant Examiner(s): Weatherby, Ellsworth
• Application Number:
  US12/858,242
• Publication Number:
  US 20110040190A1
• Time in Patent Office: 1,771 Days
• Field of Search: 600/439, 601 2- 3
• US Class Current: 1/1
• CPC Class Codes: A61B 17/2251 characterised by coupling elements between the apparatus, e.g. shock wave apparatus or locating means, and the patient, e.g. details of bags, pressure control of bag on patient
• CPC Class Codes: A61B 17/2256 with means for locating or checking the concrement, e.g. X-ray apparatus, imaging means A61B17/2255 takes precedence
• CPC Class Codes: A61B 2017/00274 Prostate operation, e.g. prostatectomy, turp, bhp treatment
• CPC Class Codes: A61B 2017/2253 using a coupling gel or liquid
• CPC Class Codes: A61B 2018/00547 Prostate
• CPC Class Codes: A61B 2090/378 using ultrasound
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/4272 involving the acoustic interface between the transducer and the tissue
• CPC Class Codes: A61B 8/4281 characterised by sound-transmitting media or devices for coupling the transducer to the tissue
• CPC Class Codes: A61B 8/445 Details of catheter construction
• CPC Class Codes: A61N 2007/0039 using microbubbles
• CPC Class Codes: A61N 2007/0043 intra-cavitary
• CPC Class Codes: A61N 7/00 Ultrasound therapy lithotripsy A61B17/22, A61B17/225; massage using supersonic vibration A61H23/00 ; using ultrasound for introducing media into the body A61M37/0092

Abstract

A medical imaging and therapy device is provided that may include any of a number of features. One feature of the device is that it can acoustically couple an ultrasound therapy transducer to a patient. In some embodiments, the medical imaging and therapy device is configured to conform to the anatomy of a patient'"'"'s perineal area to acoustically couple an ultrasound therapy transducer to the patient for treatment of BPH. The medical imaging and therapy device can be used in therapeutic applications such as Histotripsy, Lithotripsy, and HIFU, for example. Methods associated with use of the medical imaging and therapy device are also covered.

Claims

1. An ultrasound therapy device, comprising:

a frame configured to conform to and provide a liquid seal against a patient'"'"'s skin, the frame defining an open aperture;

a rectal imaging probe configured to image a patient'"'"'s prostate;

a reservoir portion configured to hold an acoustic coupling medium, the reservoir portion being configured to provide the acoustic coupling medium in direct contact with the patient'"'"'s skin through the open aperture, the reservoir portion further comprising a sheath configured to receive the rectal imaging probe; and

an ultrasound transducer coupled to the frame and in acoustic communication with the acoustic coupling medium, wherein movement of the ultrasound transducer relative to the frame maintains acoustic communication between the ultrasound transducer and the acoustic coupling medium.

2. The ultrasound therapy device of claim 1 wherein the frame is sized and shaped to conform to a male patient'"'"'s anatomy surrounding the perineum.

3. The ultrasound therapy device of claim 2 further comprising a sling configured to hold the patient'"'"'s scrotum away from the perineum.

4. The ultrasound therapy device of claim 1 further comprising an opening in the reservoir portion configured to expose the acoustic coupling medium to air.

5. The ultrasound therapy device of claim 1 wherein the acoustic coupling medium comprises a degassed water.

6. The ultrasound therapy device of claim 1 wherein the frame is configured to be secured to the patient with an adhesive.

7. The ultrasound therapy device of claim 1 wherein the frame is configured to be secured to the patient with a strap.

8. The ultrasound therapy device of claim 1 wherein the frame comprises a wearable garment.

9. The ultrasound therapy device of claim 8 wherein the wearable garment is configured to provide a liquid seal against the patient'"'"'s skin near the patient'"'"'s waist and near the patient'"'"'s legs.

10. The ultrasound therapy device of claim 8 wherein the wearable garment is configured to provide a liquid seal against the patient'"'"'s skin around the patient'"'"'s perineum.

11. The ultrasound therapy device of claim 1 further comprising a remote reservoir configured to receive the acoustic coupling medium from the reservoir portion when the reservoir portion is compressed and to deliver the acoustic coupling medium to the reservoir portion when the reservoir portion is expanded.

12. The ultrasound therapy device of claim 1 wherein the ultrasound transducer is configured to deliver a histotripsy pulse to the patient'"'"'s prostate.

13. The ultrasound therapy device of claim 1 wherein the ultrasound transducer is configured to form cavitation bubbles in the patient'"'"'s prostate.

14. The ultrasound therapy device of claim 1 wherein the ultrasound transducer is configured to deliver acoustic pulses that operate at a frequency between 50 KHz and 5 MHz, having a pulse intensity with a peak negative pressure of 8-25 MPa, a peak positive pressure of more than 10 MPa, a pulse length shorter than 50 cycles, a duty cycle between 0.1% and 5%, and a pulse repetition frequency of less than 5 KHz.

15. The ultrasound therapy device of claim 1 wherein the sheath extends through the reservoir portion and provides a liquid seal barrier for inserting the rectal imaging probe into the patient'"'"'s rectum.