Sample metering device and assay device with integrated sample dilution
First Claim
1. A sensor cartridge for sensing at least one analyte in a sample, comprising:
- at least one sensor in an analysis conduit;
a sample chamber between a sample entry port and a sample extraction unit;
a diluent package containing a diluent;
a diluent conduit configured for transporting diluent from the diluent package directly to the sample extraction unit; and
a pump configured to transfer said diluent through said diluent conduit, over and/or through said sample extraction unit, and into said analysis conduit.
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Accused Products
Abstract
In one embodiment, the invention is to a sample metering device, comprising a sample holding chamber oriented between a sample entry port and a sample extraction unit, wherein a portion of said extraction unit defines a metered volume of a sample. A diluent may be transported over and/or through the extraction unit to form a diluted sample for sample analysis. In another embodiment, the invention is to an apparatus and method for rapid determination of analytes in liquid samples by various assays including immunoassays incorporating a sample dilution feature, capable of being used in the point-of-care diagnostic field is provided. The devices and methods of the invention preferably are well-suited for high range sample dilution.
30 Citations
19 Claims
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1. A sensor cartridge for sensing at least one analyte in a sample, comprising:
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at least one sensor in an analysis conduit; a sample chamber between a sample entry port and a sample extraction unit; a diluent package containing a diluent; a diluent conduit configured for transporting diluent from the diluent package directly to the sample extraction unit; and a pump configured to transfer said diluent through said diluent conduit, over and/or through said sample extraction unit, and into said analysis conduit. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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Specification