Secure liquid drug dispenser and method for delivering liquid medication

• US 9,061,879 B2
• Filed: 03/29/2010
• Issued: 06/23/2015
• Est. Priority Date: 03/29/2010
• Status: Active Grant

• Current Assignee: Ethimedix SA
• Original Assignee: Ethimedix SA
• Inventors: Patthey, Ren
• Primary Examiner(s): Shaver, Kevin P
• Assistant Examiner(s): NICHOLS II, ROBERT K
• Application Number:
  US13/635,695
• Publication Number:
  US 20130068790A1
• Time in Patent Office: 1,912 Days
• Field of Search: 222/394, 222/386.5, 222/399, 222/95, 222/105, 222/400.5, 222/61, 222/400.8
• US Class Current: 1/1
• CPC Class Codes: A61J 7/0076 Medicament distribution means with pill counting devices A61J7/02; with time indication A61J7/04; containers or packages with special means for dispensing contents B65D83/00
• CPC Class Codes: A61J 7/0409 with timers
• CPC Class Codes: A61J 7/0445 for preventing drug dispensing during a predetermined time period
• CPC Class Codes: A61J 7/0481 working on a schedule basis
• CPC Class Codes: B67D 7/08 Arrangements of devices for controlling, indicating, metering or registering quantity or price of liquid transferred arrangement of flow- or pressure-control valves B67D7/36; computing, calculating, counting G06; coin-freed apparatus for dispensing fluids G07F13/00; prepayment devices for metering liquids G07F15/00

Abstract

A secure liquid drug dispenser for delivering pre-determined doses of medication for oral administration, including an airtight container (1) pressurized thanks to a micro pump (28) defining a pressurized area (10) in which a flexible bag (13) containing the drug to deliver is attached, the flexible bag (13) being connected to a valve (20) located within a second non pressurized area (21) of the container for delivering doses of drug trough a delivery port (23). A microcontroller within the pressurized area (21) controls the opening of the valve for precise delivery of drug doses and monitors the pressure within the pressurized area (21). The drug dispenser is further equipped with a neutralization subsystem (16) for inactivating the medication contained in the flexible bag (13) and biometrics elements are provided to identify the patient. A method of delivering doses of liquid medication is also disclosed.

Claims

1. A secure drug dispenser for delivering doses of a liquid medication for oral administration, comprising:

a pressurized airtight container (1) defining a pressurized area (10) in which a flexible bag (13) containing the medication to deliver is arranged, said flexible bag (13) being connected to a valve (20) for delivering a dose through a delivery port (23);

a pressure sensor (27); and

within the pressurized area (10), a power supply subsystem (38) and a microcontroller for controlling the valve (20) and for monitoring the pressure within the pressurized area (10).

2. The drug dispenser according to claim 1, wherein the flexible bag (13) containing the liquid medication to deliver comprises a subsystem (16) for neutralizing the medication, said subsystem being activated by the microcontroller (33) when a pressure drop is detected.

3. The drug dispenser according to claim 1, further comprising a micro pump (28) that is adapted to pressurize the pressurized area (10) of the container.

4. The drug dispenser according to claim 1, further comprising biometric identification means (30,35) for authenticating a patient accessing the dispenser.

5. The drug dispenser according to claim 1, wherein the pressurized area (10) of the container (1) is closed with a base plate (3) and locked with a locking mechanism (7,9) that may only be actuated by the microcontroller (33).

6. The drug dispenser according to claim 1, wherein the neutralization subsystem comprises a closed glass pipe (40) filled with a neutralizing material (45) compressed under the action of a spring (41) and an electric actuator connected to a lever system (43,44) for breaking the glass pipe (40) upon activation of the electric actuator.

7. The drug dispenser according to claim 1, wherein the power supply subsystem (38) comprises at least two sets (12) of batteries (46), and a switch allowing the microcontroller (33) to selectively activate one of the sets (12).

8. The drug dispenser according to claim 1, wherein the medication delivered is a solution of morphine sulphate and the neutralizing material (45) comprises high quality active carbon with particle having a diameter ≦

40 μ

m.

9. The drug dispenser according to claim 1, wherein the valve (20) is a bi-stable solenoid valve.

10. The drug dispenser according to claim 1, further comprising a wireless secured communication system that permits remote controlling and monitoring of the drug dispenser.

11. The drug dispenser according to claim 1, further comprising a hollow handle (26) fixed to a body of the container (1) and a recess (25) for holding a delivery cup (24), and wherein spare delivery cups (24) are arranged in a hollow portion of the handle (26).

12. A method of delivering a dose of liquid medication for oral administration to a patient comprising the steps of:

introducing a flexible bag (13) containing a solution of liquid medication to deliver within the airtight area (10) of the drug dispenser according to claim 1,

locking and pressurizing the container (1),

memorizing biometric parameters of a patient,

downloading a prescription scheme into the memory of the microcontroller (33),

monitoring the pressure within the container,

responding to a patient'"'"'s solicitation by acquiring his biometric parameters and comparing said parameters to those stored in memory,

verifying the timing set in the prescription scheme,

in case of a positive match of the last two steps, delivering a dose of medication in conformity with the dosage defined in the prescription scheme,

resetting the timing parameters and if necessary activating the pump to compensate the pressure loss induced by the delivery of the dose.

13. The method according to claim 12, further comprising activating the neutralization subsystem in case of a sudden pressure loss or a temperature decrease up to the frozen point of the liquid solution.