Biosensor, biosensor chip and biosensor device

• US 9,068,931 B2
• Filed: 10/10/2014
• Issued: 06/30/2015
• Est. Priority Date: 07/02/2002
• Status: Active Grant

• Current Assignee: PHC Holdings Corporation
• Original Assignee: Panasonic Healthcare Holdings Co., Ltd.
• Inventors: Ueno, Hiroya, Nakatsuka, Junji
• Primary Examiner(s): Noguerola, Alexander
• Application Number:
  US14/512,243
• Publication Number:
  US 20150072402A1
• Time in Patent Office: 263 Days
• US Class Current: 1/1
• CPC Class Codes: C12Q 1/001 Enzyme electrodes
• CPC Class Codes: G01N 27/30 Electrodes, e.g. test electrodes; Half-cells G01N27/414 takes precedence
• CPC Class Codes: G01N 27/307 Disposable laminated or multilayered electrodes G01N27/3272 takes precedence
• CPC Class Codes: G01N 27/327 Biochemical electrodes , e.g. electrical or mechanical details for in vitro measurements
• CPC Class Codes: G01N 27/3271 Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood amperometry per se G01N27/49; aspects concerning the enzyme reagent C12Q1/001
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52
• CPC Class Codes: G01N 27/3273 Devices therefor, e.g. test element readers, circuitry details not specific to biochemical electrodes G01N33/4875
• CPC Class Codes: G01N 27/416 Systems G01N27/27 takes precedence
• CPC Class Codes: G01R 19/0092 measuring current only all subgroups of G01R19/00 take precedence

Abstract

A biosensor includes a working electrode 101, a counter electrode 102 opposing the working electrode 101, a working electrode terminal 103 and a working electrode reference terminal 10 connected to the working electrode 101 by wires, and a counter electrode terminal 104 connected to the counter electrode 102 by a wire. By employing a structure with at least three electrodes, it is possible to assay a target substance without being influenced by the line resistance on the working electrode side.

Claims

1. A device configured to be connected to a biosensor that has a working electrode and a counter electrode that are disposed on a proximal end, first and second conductive lines connected to the working electrode and extending to a distal end of the biosensor, and third and fourth conductive lines connected to the counter electrode and extending to the distal end of the biosensor;

the device comprising;

a first terminal that is configured to be connected to the first conductive line of the biosensor;

a second terminal that is configured to be connected to the second conductive line of the biosensor;

a third terminal that is configured to be connected to the third conductive line of the biosensor; and

a fourth terminal that is configured to be connected to the fourth conductive line of the biosensor;

wherein the first and second terminals are disposed on one side of a center line and the third and fourth terminals are disposed on the other side of the centerline, the center line extending between the proximal end and the distal end of the biosensor when the biosensor is connected to the device; and

,

a measurement circuit for controlling a voltage between the working electrode and the counter electrode using a voltage at the second terminal and a voltage at the fourth terminal and for detecting a current between the working electrode and the counter electrode using a current flowing at the first terminal or the third terminal.

2. The device of claim 1, comprising an amplifier having high input impedance, wherein the second terminal is coupled to an input of the amplifier.

3. The device of claim 1, comprising an amplifier having high input impedance, wherein the fourth terminal is coupled to an input of the amplifier.

4. The device of claim 1, wherein substantially no current flows through the second terminal and the fourth terminal when a current flows at the first terminal or the third terminal.

5. The device of claim 1, wherein the first terminal is adjacent to the second terminal.

6. The device of claim 1, wherein the third terminal is adjacent to the fourth terminal.

7. The device of claim 1, wherein the first terminal is between the second terminal and the third terminal.

8. The device of claim 1, wherein the third terminal is between the first terminal and the fourth terminal.

9. The device of claim 1, wherein the second terminal, the first terminal, the third terminal, and the fourth terminal are arranged in this order.