Method and apparatus for identifying cardiac risk
First Claim
1. A method for computing a cardiac-based metric for use as a predictor of cardiac risk, the method comprising:
- for each of a plurality of cardiac cycles of a subject, identifying the end of a mechanical systole based upon an acoustical vibration associated with closure of an aortic valve during the cardiac cycle; and
computing the cardiac-based metric based upon, for each of the plurality of cardiac cycles, a time difference between the end of the mechanical systole and the end of an electrical systole of an electrocardiogram (ECG) signal for the cardiac cycle.
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Accused Products
Abstract
A cardiac-based metric is computed based upon characteristics of a subject'"'"'s cardiac function. In accordance with one or more embodiments, the end of a mechanical systole is identified for each of a plurality of cardiac cycles of a subject, based upon an acoustical vibration associated with closure of an aortic valve during the cardiac cycle. The end of an electrical systole of an electrocardiogram (ECG) signal for each cardiac cycle is also identified. A cardiac-based metric is computed, based upon a time difference between the end of the electrical systole and the end of the mechanical systole, for the respective cardiac cycles.
51 Citations
20 Claims
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1. A method for computing a cardiac-based metric for use as a predictor of cardiac risk, the method comprising:
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for each of a plurality of cardiac cycles of a subject, identifying the end of a mechanical systole based upon an acoustical vibration associated with closure of an aortic valve during the cardiac cycle; and computing the cardiac-based metric based upon, for each of the plurality of cardiac cycles, a time difference between the end of the mechanical systole and the end of an electrical systole of an electrocardiogram (ECG) signal for the cardiac cycle. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. An apparatus for computing a cardiac-based metric for use as a predictor of cardiac risk comprising:
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a first module configured and arranged to, for each of a plurality of cardiac cycles of a subject, identify the end of a mechanical systole based upon an acoustical vibration associated with closure of an aortic valve during the cardiac cycle; and a second module configured and arranged to compute a cardiac-based metric based upon, for each of the plurality of cardiac cycles, a time difference between the end of the mechanical systole and the end of an electrical systole of an electrocardiogram (ECG) signal for the cardiac cycle. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19)
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20. A method comprising:
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for each of a plurality of cardiac cycles of a subject, identifying the end of a mechanical systole based upon an acoustical vibration associated with closure of an aortic valve during the cardiac cycle; and computing a cardiac-based metric indicative of arrhythmic risk by; computing beat-to-beat values of a subject'"'"'s cardiac function based on, for each of the plurality of cardiac cycles, a time difference between the end of the mechanical systole and the end of an electrical systole of an electrocardiogram (ECG) signal for the cardiac cycle, computing a time series for each of successive lags of the beat-to-beat values by applying a low-pass filter and decimator to the beat-to-beat values, and evaluating the arrhythmic risk based upon a trend of the variability of the time series.
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Specification