Implantable prosthesis

• US 9,072,586 B2
• Filed: 10/02/2009
• Issued: 07/07/2015
• Est. Priority Date: 10/03/2008
• Status: Active Grant

• Current Assignee: C.R. Bard, Inc. (Becton, Dickinson & Co)
• Original Assignee: C.R. Bard, Inc. (Becton, Dickinson & Co)
• Inventors: Ranucci, Debra J., Hamlin, Tami L., Staudenmeier, Marianne, Tessier, Philip A., Tomlin, Damian H.
• Primary Examiner(s): Anderson, Gregory
• Assistant Examiner(s): LAUER, CHRISTINA C
• Application Number:
  US13/122,257
• Publication Number:
  US 20110288567A1
• Time in Patent Office: 2,104 Days
• Field of Search: 606/151, 623/23.72, 600/30
• US Class Current: 1/1
• CPC Class Codes: A61B 2090/0816 for preventing adhesion
• CPC Class Codes: A61F 2/0063 Implantable repair or support meshes, e.g. hernia meshes
• CPC Class Codes: A61F 2250/0051 differing in tissue ingrowth capacity, e.g. made from both ingrowth-promoting and ingrowth-preventing parts

Abstract

An implantable prosthesis is provided for repairing an anatomical defect, such as a tissue or muscle defect, that promotes tissue of muscle ingrowth into the prosthesis and subsequently strengthens the area of the defect. The prosthesis is easy to manipulate and may be designed to minimize the incidence of postoperative adhesions between a portion of the prosthesis and surrounding tissue or organs. The prosthesis may include one or more layers of biologically compatible material that is suitable for repairing a defect. The prosthesis may include a support assembly to facilitate manipulation and deployment of the prosthesis. The support assembly may include a stiffening member that is surrounded by material that separates the stiffening member from the layer of material. The stiffening member may be located in a sleeve of material, such as mesh fabric. The stiffening member may be formed from a resorbable material.

Claims

1. An implantable prosthesis comprising:

a first layer of material having an outer periphery;

a second layer of material attached to the first layer, the second layer having an outer periphery; and

a support assembly located between the first and second layers of material and confined within the outer peripheries thereof, the support assembly including a stiffening member and a sleeve of material that separates the stiffening member from the first and second layers, the stiffening member located within and surrounded by the sleeve of material.

2. The implantable prosthesis of claim 1, wherein the first layer of material is configured to allow tissue ingrowth and the second layer of material is configured to inhibit the formation of adhesions thereto.

3. The implantable prosthesis of claim 1, wherein the stiffening member is formed of an absorbable material.

4. The implantable prosthesis of claim 3, wherein the stiffening member is formed of polydioxanone.

5. The implantable prosthesis of claim 3, wherein the sleeve is formed of an absorbable material.

6. The implantable prosthesis of claim 5, wherein the sleeve is formed of a material that is absorbable slower than the stiffening member.

7. The implantable prosthesis of claim 1, wherein the stiffening member includes a continuous ring.

8. The implantable prosthesis of claim 1, wherein the stiffening member is resilient.

9. The implantable prosthesis of claim 1, wherein the sleeve is configured to allow tissue ingrowth therethrough.

10. The implantable prosthesis of claim 9, wherein the sleeve is formed of a mesh fabric.

11. The implantable prosthesis of claim 1, wherein the sleeve is formed of a tubular fabric.

12. The implantable prosthesis of claim 1, further comprising a barrier layer that inhibits the formation of adhesions thereto, the barrier layer being attached to one of the first layer, the second layer and the support assembly.

13. The implantable prosthesis of claim 1, wherein at least one pocket is formed between the first and second layers.

14. The implantable prosthesis of claim 1, wherein the first and second layers are formed of mesh fabric.

15. The implantable prosthesis of claim 14, wherein the mesh fabric includes a knitted polypropylene mesh.

16. The implantable prosthesis of claim 1, wherein the first layer of material includes interstices having a first size and the sleeve includes interstices having a second size that is smaller than the first size.

17. An implantable prosthesis comprising:

a first layer of mesh having an outer periphery;

a second layer of mesh attached to the first layer of mesh with at least one pocket therebetween, the second layer of mesh having an outer periphery; and

a support assembly located between the first and second mesh layers, the support assembly including a stiffening member that is surrounded by material located between the stiffening member and the first and second layers of mesh, the support assembly confined within the outer peripheries of the first and second mesh layers.

18. The implantable prosthesis of claim 17, wherein the support assembly includes a sleeve of material that surrounds the stiffening member, the stiffening member being located in the sleeve.

19. The implantable prosthesis of claim 18, wherein the sleeve is configured to allow tissue ingrowth therein.

20. The implantable prosthesis of claim 19, wherein the sleeve includes a mesh fabric.

21. The implantable prosthesis of claim 20, wherein the sleeve is formed of a knitted polypropylene mesh.

22. The implantable prosthesis of claim 18, wherein the sleeve includes first and second rings of material that are joined together, the stiffening member being located between the first and second rings.

23. The implantable prosthesis of claim 18, wherein the sleeve includes a tubular fabric, the stiffening member being located within the tubular fabric.

24. The implantable prosthesis of claim 18, wherein the first layer of material includes interstices having a first size and the sleeve includes interstices having a second size that is smaller than the first size.

25. The implantable prosthesis of claim 18, wherein the sleeve is formed of an absorbable material.

26. The implantable prosthesis of claim 25, wherein the stiffening member is formed of an absorbable material and the sleeve is formed of a material that is absorbable slower than the stiffening member.

27. The implantable prosthesis of claim 17, wherein the stiffening member is formed of an absorbable material.

28. The implantable prosthesis of claim 27, wherein the stiffening member is formed of polydioxanone.

29. The implantable prosthesis of claim 17, wherein the stiffening member includes a continuous ring.

30. The implantable prosthesis of claim 17, wherein the stiffening member is resilient.

31. The implantable prosthesis of claim 17, further comprising a barrier layer that inhibits the formation of adhesions thereto, the barrier layer being attached to one of the first layer, the second layer and the support assembly.

32. The implantable prosthesis of claim 17, wherein the first layer includes an access opening to the at least one pocket.

33. An implantable prosthesis comprising:

a first layer of mesh fabric having an outer periphery;

a second layer of mesh fabric attached to the first layer of mesh fabric with at least one pocket therebetween, the second layer of mesh fabric having an outer periphery;

a support assembly located between the first and second layers of mesh fabric and confined within the outer peripheries thereof, the support assembly including an absorbable stiffening member surrounded with a sleeve of mesh fabric; and

a barrier layer that inhibits the formation of adhesions thereto, the barrier layer being attached to at least one of the first layer, the second layer and the support assembly.

34. The implantable prosthesis of claim 33, wherein the mesh fabric is configured to allow tissue ingrowth therein.

35. The implantable prosthesis of claim 34, wherein the mesh fabric includes a knitted polypropylene mesh.

36. The implantable prosthesis of claim 33, wherein the sleeve includes first and second rings of mesh fabric that are joined together, the stiffening member being located between the first and second rings.

37. The implantable prosthesis of claim 33, wherein the sleeve includes a tubular fabric, the stiffening member being located within the tubular fabric.

38. The implantable prosthesis of claim 33, wherein the stiffening member is formed of polydioxanone.

39. The implantable prosthesis of claim 33, wherein the stiffening member includes a continuous ring.

40. The implantable prosthesis of claim 33, wherein the stiffening member is resilient.

41. The implantable prosthesis of claim 33, wherein the first layer of material includes interstices having a first size and the sleeve includes interstices having a second size that is smaller than the first size.

42. The implantable prosthesis of claim 33, wherein the sleeve is formed of an absorbable material.

43. The implantable prosthesis of claim 42, wherein the sleeve is formed of a material that is absorbable slower than the stiffening member.

44. The implantable prosthesis of claim 33, wherein the first layer includes an access opening to the at least one pocket.