Compositions and methods for therapeutic delivery with frozen particles
First Claim
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1. A therapeutic composition, comprising:
- one or more frozen hydrogen oxide particles less than 200 micrometers in size and coated with a specific cell receptor;
the one or more frozen hydrogen oxide particles each further defining at least two cavities, the first cavity containing at least one anti-tumor agent, including at least one of an alkylating agent, antimetabolite, anthracycline, plant alkaloid, topoisomerase inhibitor, monoclonal antibody, or tyrosine kinase inhibitor;
and the second cavity containing one or more of a cytokine, chemokine, anti-angiogenic factor, anti-inflammatory agent, vaccine, hormone, or radioactive agent.
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Abstract
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.
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Citations
33 Claims
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1. A therapeutic composition, comprising:
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one or more frozen hydrogen oxide particles less than 200 micrometers in size and coated with a specific cell receptor;
the one or more frozen hydrogen oxide particles each further defining at least two cavities, the first cavity containing at least one anti-tumor agent, including at least one of an alkylating agent, antimetabolite, anthracycline, plant alkaloid, topoisomerase inhibitor, monoclonal antibody, or tyrosine kinase inhibitor;and the second cavity containing one or more of a cytokine, chemokine, anti-angiogenic factor, anti-inflammatory agent, vaccine, hormone, or radioactive agent. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33)
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Specification