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Optical space-time coding technique in microfluidic devices

  • US 9,074,978 B2
  • Filed: 07/12/2012
  • Issued: 07/07/2015
  • Est. Priority Date: 07/12/2011
  • Status: Active Grant
First Claim
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1. A microfluidic device for optical detection of particles, comprising:

  • a substrate;

    a microfluidic channel formed on the substrate and structured to carry a fluid sample containing particles, the microfluidic channel structured to transmit a probe light; and

    a mask formed on one side of the microfluidic channel and structured to include a pattern of openings along the microfluidic channel, wherein at least two of the openings have varying longitudinal and transverse dimensions with respect to a fluid flow direction across the microfluidic channel, and wherein the pattern of openings encodes a waveform on the probe light that transmits through the microfluidic channel to allow optical detection of a position of a particle in at least two dimensions in the microfluidic channel.

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