Method and system for patient-specific modeling of blood flow
First Claim
1. A system for determining cardiovascular information for a patient, the system comprising:
- at least one computer system configured to;
receive patient-specific data regarding a geometry of an anatomical structure of the patient, the anatomical structure including at least a portion of a plurality of coronary arteries emanating from the patient'"'"'s aorta;
create a three-dimensional model representing the anatomical structure using the patient-specific data;
estimate a mass or volume of myocardial tissue of the patient using one or both of the received patient-specific data and the created three-dimensional model;
create a blood flow model defining blood flow through the anatomical structure of the patient and modify the created blood flow model using, at least in part, a coronary blood flow associated with the estimated mass or volume of myocardial tissue of the patient; and
determine at least one blood flow characteristic within the anatomical structure using the three-dimensional model and the blood flow model.
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Accused Products
Abstract
Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient'"'"'s heart, and create a three-dimensional model representing at least a portion of the patient'"'"'s heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient'"'"'s heart and determine a fractional flow reserve within the patient'"'"'s heart based on the three-dimensional model and the physics-based model.
243 Citations
19 Claims
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1. A system for determining cardiovascular information for a patient, the system comprising:
at least one computer system configured to; receive patient-specific data regarding a geometry of an anatomical structure of the patient, the anatomical structure including at least a portion of a plurality of coronary arteries emanating from the patient'"'"'s aorta; create a three-dimensional model representing the anatomical structure using the patient-specific data; estimate a mass or volume of myocardial tissue of the patient using one or both of the received patient-specific data and the created three-dimensional model; create a blood flow model defining blood flow through the anatomical structure of the patient and modify the created blood flow model using, at least in part, a coronary blood flow associated with the estimated mass or volume of myocardial tissue of the patient; and determine at least one blood flow characteristic within the anatomical structure using the three-dimensional model and the blood flow model. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A computer-implemented method for determining patient-specific cardiovascular information using at least one computer system, the method comprising:
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receiving, at the at least one computer system, patient-specific data regarding a geometry of an anatomical structure of the patient, the anatomical structure including at least a portion of a plurality of coronary arteries emanating from the patient'"'"'s aorta; creating, using at least one computer system, a three-dimensional model representing the anatomical structure using the patient-specific data; estimating a mass or volume of myocardial tissue of the patient using one or both of the received patient-specific data and the created three-dimensional model; creating, using at least one computer system, a blood flow model defining blood flow through the anatomical structure of the patient and modifying the created blood flow model using, at least in part, a coronary blood flow associated with the estimated mass or volume of myocardial tissue of the patient; and determining, using at least one computer system, at least one blood flow characteristic within the anatomical structure using the three-dimensional model and the blood flow model. - View Dependent Claims (13, 14, 15, 16)
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17. A non-transitory computer readable medium for use on at least one computer system containing computer-executable programming instructions for performing a method for determining patient-specific cardiovascular information, the method comprising:
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receiving patient-specific data regarding a geometry of an anatomical structure of the patient, the anatomical structure including at least a portion of a plurality of coronary arteries emanating from the patient'"'"'s aorta; creating a three-dimensional model representing the anatomical structure using the patient-specific data; estimating a mass or volume of myocardial tissue of the patient using one or both of the received patient-specific data and the created three-dimensional model; creating a blood flow model defining blood flow through the anatomical structure of the patient and modifying the created blood flow model using, at least in part, a coronary blood flow associated with the estimated mass or volume of myocardial tissue of the patient; and determining at least one blood flow characteristic within the anatomical structure using the three-dimensional model and the blood flow model. - View Dependent Claims (18, 19)
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Specification