Administration device having patient state monitor

• US 9,078,965 B2
• Filed: 10/08/2010
• Issued: 07/14/2015
• Est. Priority Date: 04/11/2008
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diagnostics International AG (Roche Holding AG)
• Inventors: Van der Helm, Wim, Remde, Axel, Friedli, Kurt
• Primary Examiner(s): Sirmons, Kevin C
• Assistant Examiner(s): PATEL, SHEFALI DILIP
• Application Number:
  US12/901,090
• Publication Number:
  US 20110082445A1
• Time in Patent Office: 1,740 Days
• Field of Search: 604/890.1, 604/65, 604/66, 604/67, 604/131, 604/151, 604/245
• US Class Current: 1/1
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/332 Force measuring means
• CPC Class Codes: A61M 2205/3327 Measuring
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2230/63 Motion, e.g. physical activity
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00

Abstract

Embodiments disclosed herein include systems and methods for administering a drug over a time period. One embodiment of a system includes an administration unit, a housing that houses the administration unit, and a controller unit adapted to receive an alarm triggering signal. Also included in some embodiments is an alarming unit that is adapted to generate an alarm signal on reception of the alarm triggering signal. Some embodiments include a patient state monitor that includes a motion-sensitive sensor unit that is reactive on patient motion. The patient state monitor may be adapted to process a sensor signal generated by the motion-sensitive sensor unit. The patient state monitor may also be adapted to transmit the alarm triggering signal to the controller unit if a patient motion level is below a predefined motion level, as determined by a length of time without patient motion.

Claims

1. An administration device for administration of a liquid drug over an extended time period to a patient, comprising:

an administration unit;

a housing that houses the administration unit, the housing being adapted to be carried by the patient over the extended time period;

a controller unit adapted to control operation of the administration unit, the controller unit further adapted to receive an alarm triggering signal;

an alarming unit that is coupled to the controller unit, the alarming unit adapted to generate an alarm signal on reception of the alarm triggering signal by the controller unit; and

a patient state monitor that includes a motion-sensitive sensor unit, the motion-sensitive sensor unit being reactive on patient motion, the patient state monitor being adapted to process a sensor signal (SS) generated by the motion-sensitive sensor unit, and a counter unit adapted to generate the alarm triggering signal and to transmit the alarm triggering signal to the controller unit if processing of the sensor signal (SS) indicates a patient motion level is below a predefined motion level, the predefined motion level being defined by a length of time-periods without patient motion that can be expected for a conscious human.

2. The administration device of claim 1, wherein the motion-sensitive sensor unit is coupled to a motion sensor unit housing, the motion sensor unit housing being separate from the housing.

3. The administration device of claim 1, wherein the motion-sensitive sensor unit includes at least one of the following:

a tilt sensor, a vibration sensor, a shock sensor, and an acceleration sensor.

4. The administration device of claim 1, wherein the motion-sensitive sensor unit includes at least one binary switching sensor.

5. The administration device of claim 1, wherein the patient state monitor includes an energy storage, the motion-sensitive sensor unit being adapted to modify an energy (E) stored by the energy storage.

6. The administration device of claim 1, wherein the controller unit is adapted to control the administration unit to stop the drug administration on reception of the alarm triggering signal.

7. The administration device of claim 1, wherein the counter unit is adapted to count a number (N) of consecutive monitoring intervals without substantive patient motion.

8. The administration device of claim 7, wherein the counter unit is further adapted to generate the alarm triggering signal if the number (N) of consecutive monitoring intervals without substantive patient motion equals a threshold number (TN).

9. An administration device for administration of a liquid drug over an extended time period to a patient, comprising:

an administration unit;

a housing that houses the administration unit, the housing being adapted to be carried by the patient over the extended time period;

a controller unit adapted to control operation of the administration unit, the controller unit further adapted to receive an alarm triggering signal;

an alarming unit that is coupled to the controller unit, the alarming unit adapted to generate an alarm signal on reception of the alarm triggering signal by the controller unit; and

a patient state monitor that includes an energy storage, a motion-sensitive sensor unit being reactive on patient motion and switchably connected to the energy storage, a voltage threshold detector operably coupled to the energy storage and a counter unit, wherein the patient state monitor being adapted to process a binary output of the voltage threshold detector to the counter unit, such that the counter unit is adapted to count a number (N) of consecutive monitoring intervals without substantial patient motion, compare the number (N) of consecutive monitoring intervals without substantial patient motion with a threshold number (TN), and if a capacitor voltage is below a threshold voltage the counter unit is reset to zero, otherwise the number (N) of consecutive monitoring intervals without substantial patient motion is incremented by one.

10. The administration device of claim 9, wherein the motion-sensitive sensor unit is coupled to a motion sensor unit housing, the motion sensor unit housing being separate from the housing.

11. The administration device of claim 9, wherein the motion-sensitive sensor unit includes at least one binary switching sensor adapted to modify an energy (E) stored by the energy storage when the at least one binary switching sensor is in a closed state.

12. The administration device of claim 9, wherein the energy storage is a capacitor of a capacity (C).

13. The administration device of claim 9, wherein the controller unit is adapted to control the administration unit to stop the drug administration on reception of the alarm triggering signal.

14. The administration device of claim 9, wherein the patient state monitor being further adapted to generate the alarm triggering signal if no patient motion has occurred for the threshold number (TN) based on an alarming time interval (AT) which is given by a product of a monitoring length (MT) and the threshold number (TN).

15. The administration device of claim 14, wherein the counter unit further comprises a comparator, the comparator being adapted to generate the alarm triggering signal to the controller unit.